Barrier-free, open-top microfluidic chip for generating two distinct, interconnected 3D microvascular networks.

Developing microphysiological cell culture platforms with a three-dimensional (3D) microenvironment has been a significant advancement from traditional monolayer cultures. Still, most of the current microphysiological platforms are limited in closed designs, i.e.

Reactive laser interference patterning on titanium and zinc in high pressure CO.

Direct laser interference patterning (DLIP) is a versatile technique for surface patterning that enables formation of micro-nano sized periodic structures on top of the target material. In this study, DLIP in high pressure, supercritical and liquid CO by 4-beam DLIP was used to pattern titanium and zinc targets. Field emission scanning electron microscopy, atomic force microscopy, and X-ray photoelectron spectroscopy was used to characterize the patterned surfaces.

Carbon coated TiO nanoparticles prepared by pulsed laser ablation in liquid, gaseous and supercritical CO.

We report on the synthesis of TiO nanoparticles using nanosecond pulse laser ablation of titanium in liquid, gaseous and supercritical CO. The produced particles were observed to be mainly anatase-TiO with some rutile-TiO. In addition, the particles were covered by a carbon layer.

Comparative analysis of tissue reconstruction algorithms for 3D histology.

Motivation: Digital pathology enables new approaches that expand beyond storage, visualization or analysis of histological samples in digital format. One novel opportunity is 3D histology, where a three-dimensional reconstruction of the sample is formed computationally based on serial tissue sections. This allows examining tissue architecture in 3D, for example, for diagnostic purposes.