Publications by authors named "Joris C W Haest"

Article Synopsis
  • - The study investigates how exercise training benefits patients with chronic heart failure (CHF) and suggests that somatosensory nerve stimulation may play a role in these benefits.
  • - Researchers conducted a randomized controlled trial involving periodic electrical somatosensory stimulation (TENS) and compared it to traditional exercise training and usual care, measuring various health indicators like blood pressure, baroreflex sensitivity, and quality of life.
  • - Results showed that the TENS group experienced improvements in health measures comparable to or better than those in the exercise training group, indicating that non-traditional exercise methods might effectively address autonomic issues in CHF patients.
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In a previous study we demonstrated that the institution of biventricular pacing in chronic heart failure (CHF) acutely facilitates the arterial baroreflex. The arterial baroreflex has important prognostic value in CHF. We hypothesized that the acute response in baroreflex sensitivity (BRS) after the institution of cardiac resynchronization therapy (CRT) has predictive value for midterm response.

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Metabolic and mechanical stress in the failing heart activates the cardiac sympathetic afferent reflex (CSAR). It has been demonstrated that cardiac resynchronization therapy (CRT) acutely reduces MSNA in clinical responders. Mechanistically, this beneficial effect might be explained by acute deactivation of the CSAR.

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Background And Aim: The oxygen uptake efficiency slope (OUES) is a novel measure of cardiopulmonary reserve. OUES is measured during an exercise test, but it is independent of the maximally achieved exercise intensity. It has a higher prognostic value in chronic heart failure (CHF) than other exercise test-derived variables such as(Equation is included in full-text article.

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