Publications by authors named "Jorinde Raasveld"
Article Synopsis
- VA-ECMO (veno-arterial extracorporeal membrane oxygenation) is used to treat severe cardiac failure and can restore overall blood circulation, but its impact on small blood vessel function is still unclear.
- A systematic review of the literature (1215 studies sourced, 11 included) focused on how VA-ECMO affects microcirculation, measuring factors like small vessel density and blood flow.
- Initial findings suggest that microcirculatory function improves within hours for survivors of cardiac events post-ECMO, but this improvement levels off; more extensive research is needed to confirm these effects over time.
Background: Reported bleeding incidences following central venous catheter (CVC) placement highly depend on methods of bleeding assessment. To determine the direction and magnitude of the bias associated with retrospective data collection, we used data from the PACER randomized controlled trial and a previous retrospective cohort study.
Study Design And Methods: A patient-level comparison of CVC-related bleeding severity was made among (1) the prospectively collected clinical bleeding assessment of the PACER trial, (2) centralized assessment of CVC insertion site photographs, and (3) retrospective chart review.
Background: Coronavirus disease 2019 (COVID-19)-induced mortality occurs predominantly in older patients. Several immunomodulating therapies seem less beneficial in these patients. The biological substrate behind these observations is unknown.
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- - This study examines survival rates and health-related quality of life (HRQOL) in patients who underwent extracorporeal membrane oxygenation (ECMO) treatment within one year of their hospital admission.
- - Out of 428 patients, 50% died within the year, but those who survived reported a good average HRQOL of 0.71 after 12 months and incurred an average total cost of $204,513, with hospital expenses being the largest portion.
- - The findings suggest that while the quality of life for ECMO survivors is favorable, the high costs raise concerns, and potential biases in follow-up data could skew results toward better health outcomes than what might be typical.
Introduction: Diffuse alveolar haemorrhage (DAH) is a potentially life-threatening disease, characterized by diffuse accumulation of red blood cells within the alveoli. It can be caused by a variety of disorders. In case DAH results in severe respiratory failure, veno-venous extracorporeal membrane oxygenation (VV-ECMO) can be required.
View Article and Find Full Text PDFBackground: Although life-saving in selected patients, ECMO treatment still has high mortality which for a large part is due to treatment-related complications. A feared complication is ischemic stroke for which heparin is routinely administered for which the dosage is usually guided by activated partial thromboplastin time (aPTT). However, there is no relation between aPTT and the rare occurrence of ischemic stroke (1.
View Article and Find Full Text PDFBackground: Deep vein thrombosis (DVT) after decannulation of extracorporeal life support (ECLS) is not uncommon. Moreover, the impact of anticoagulation and potential risk factors is unclear. Furthermore, it is unclear if cannula-associated DVT is more common in ECLS patients compared to critically ill patients without ECLS.
View Article and Find Full Text PDFPurpose: To develop evidence-based clinical practice recommendations regarding transfusion practices and transfusion in bleeding critically ill adults.
Methods: A taskforce involving 15 international experts and 2 methodologists used the GRADE approach to guideline development. The taskforce addressed three main topics: transfusion support in massively and non-massively bleeding critically ill patients (transfusion ratios, blood products, and point of care testing) and the use of tranexamic acid.
This study investigated immunological changes during an alcohol hangover, and the possible difference between hangover-resistant and hangover-sensitive drinkers in terms of immune reactivity. Using a semi-naturalistic design, N = 36 healthy social drinkers (18 to 30 years old) provided saliva samples on a control day (after drinking no alcohol) and on a post-alcohol day. Hangover severity was rated directly after saliva collection.
View Article and Find Full Text PDFIntroduction: The aim of this study was to investigate the usefulness of ethyl glucuronide (EtG) and ethyl sulfate (EtS) as biomarkers of the hangover state.
Methods: Thirty-sixhealthy social drinkers participated in this study, being of naturalistic design. Eighteen participants experience regular hangovers (the hangover group), whereas the other 18 claim to not experience a hangover (the hangover-immune group).