Publications by authors named "Jorina Schmelmer"
J Pathol Clin Res
March 2024
Article Synopsis
- Upper tract urothelial carcinoma (UTUC) is a rare and aggressive cancer that differs from more common bladder urothelial carcinoma, which has identifiable molecular subtypes and targeted therapies.
- Researchers identified protein-based subtypes of UTUC tumors using deep learning models that analyze routine histopathological slides, allowing for better prediction of tumor characteristics.
- The study found significant links between the predicted subtypes and key tumor features, including shape, histological type, and important biomarkers like PD-L1 and FGFR3 mutations, which could guide future treatment approaches.
