The Effect of Cryotherapy Application on Postoperative Pain: A Systematic Review and Meta-analysis.

Objective: To systematically review and meta-analyze whether the application of cryotherapy on closed incisions reduces postoperative pain and opioid consumption.

Background: Reduction of acute pain and opioid use is important in the postoperative phase of patient care. ''Cryotherapy'' refers to the use of low temperatures for therapeutic purposes.