Publications by authors named "Jorge Vindel-Alfageme"
The outbreak of COVID-19, led to an ongoing pandemic with devastating consequences for the global economy and human health. With the global spread of SARS-CoV-2, multidisciplinary initiatives were launched to explore new diagnostic, therapeutic, and vaccination strategies. From this perspective, proteomics could help to understand the mechanisms associated with SARS-CoV-2 infection and to identify new therapeutic options.
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- Cholestasis is a condition where bile flow from the liver to the small intestine is disrupted, leading to similar symptoms across different causes.
- Researchers analyzed the liver protein profiles of cholestatic patients and found 263 proteins that were expressed differently between healthy individuals and those with cholestasis, highlighting the molecular changes involved.
- A machine learning approach was used to identify 20 key proteins that can effectively differentiate between various types of cholestasis, offering promising insights for tailored treatment strategies in precision medicine.