Publications by authors named "Jorge Vargas Flores"
Article Synopsis
- * This study aimed to assess the immune response (specific IgG antibodies) to Aedes aegypti saliva as a potential indicator of mosquito exposure in urban areas affected by dengue.
- * Findings revealed that younger children had stronger IgG responses to the saliva, which decreased with age, and higher antibody levels correlated with greater mosquito presence, indicating that saliva antibody responses could effectively monitor human exposure to Aedes bites.
Molecular epidemiology of yellow fever in Bolivia from 1999 to 2008.
Vector Borne Zoonotic Dis
March 2011
Yellow fever (YF) is a serious public health problem in Bolivia since at least the 19th century. Surprisingly, very limited information has been made available to date regarding the genetic characterisation and epidemiology of Bolivian YF virus (YFV) strains. Here, we conducted the genetic characterization of 12 human isolates of YFV collected in Bolivia between 1999 and 2008, by sequencing and analysis of two regions of the viral genome: a fragment encoding structural proteins "PrM" (premembrane and envelope) and a distal region "EMF," spanning the end of the virus genome.
View Article and Find Full Text PDFDengue fever was first recognized in Bolivia in 1931. However, very limited information was available to date regarding the genetic characterization and epidemiology of Bolivian dengue virus strains. Here, we performed genetic characterization of the full-length envelope gene of 64 Bolivian isolates from 1998 to 2008 and investigated their origin and evolution to determine whether strains circulated simultaneously or alternatively, and whether or not multiple introductions of distinct viral variants had occurred during the period studied.
View Article and Find Full Text PDF