Publications by authors named "Jorge Spertino"

Article Synopsis
  • - A study evaluated the effectiveness and safety of dupilumab for treating bullous pemphigoid in elderly patients, with a focus on those who typically have other health issues that make standard treatments unsuitable.
  • - The results showed that 53.4% of patients achieved complete remission within 4 weeks and 95.7% by week 52, with a significant reduction in itchiness and a dramatic decrease in the need for corticosteroids.
  • - The treatment was found to be safe, with most adverse events being mild, and factors like shorter disease duration and exclusive skin involvement were linked to better treatment responses.
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Background: Dupilumab has shown to be an effective and safe treatment for patients with moderate-to-severe atopic dermatitis (AD).

Objective: To evaluate the predictive factors of response (PRF) in patients with moderate-to-severe AD treated with dupilumab.

Methods: Observational, retrospective and multicentre study conducted on adult patients diagnosed with moderate-to-severe AD treated with dupilumab, with a post-treatment follow-up of at least 16 weeks.

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Article Synopsis
  • The study looked at how patients with chronic spontaneous urticaria (CSU) respond to a medicine called omalizumab and whether they still need to take antihistamines (AH).
  • Some patients (23.5%) stopped taking AH while on omalizumab and had better results in controlling their symptoms.
  • The researchers think more studies are needed to figure out which patients can stop taking antihistamines safely while using omalizumab.
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