Brimonidine-timolol fixed combination induced granulomatous inflammation of the eye.

We report on two cases of granulomatous conjunctivitis and uveitis related with the use of a brimonidine-timolol fixed combination. Case report and a review of medical literature. A 64-year-old man was diagnosed with marked granulomatous uveitis and a 57-year-old woman was diagnosed with granulomatous conjunctivitis.

Staining of the internal limiting membrane with the use of heavy brilliant blue G.

Background: Brilliant blue G (BBG) is frequently used in chromovitrectomy to facilitate internal limiting membrane (ILM) peeling. A study was initiated to evaluate if heavy BBG is safe and effective in staining the ILM.

Methods: We studied 30 eyes, 23 with idiopathic macular holes and 7 of patients with diabetic macular edema.