Publications by authors named "Jorge Luis Fernandez Luque"
Intestinal amyloidosis is a rare and underdiagnosed systemic disease, which is characterized by the extracellular deposition of proteins that are grouped into amyloid fibers. This entity is rare and is usually a form of presentation in the context of systemic amyloidosis, the diagnosis of which is based on the presence of amyloid in histology. The clinic is usually non-specific; chronic diarrhea, weight loss, abdominal pain and bloating; Gastrointestinal bleeding is a very rare manifestation.
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- PTID accounts for around 5% of primary gastrointestinal tumors, with varying histological types showing both benign and malignant characteristics.
- A study analyzed 45 patients, primarily diagnosed at an average age of 54.2 years, with most cases (86%) found in the jejunum; GISTs, lymphomas, and adenocarcinomas were the most common tumor types identified.
- Double-balloon enteroscopy served as the primary diagnostic and treatment method, supporting various endoscopic procedures for managing these tumors, including biopsies and surgical interventions.
Unlabelled: The management of inflammatory bowel disease (IBD) is mainly medical, however, more than 70% of patients with Crohn's disease (CD) and 25% with ulcerative colitis (UC) will require surgery during their lifetime.
Objective: To evaluate medical, surgical management and evolution in patients with moderate-to-severe IBD.
Materials And Methods: Observational, descriptive, retrospective study from January 2011 to December 2019 in the Gastroenterology Service of the Guillermo Almenara Irigoyen National Hospital, Lima-Peru.
Article Synopsis
- - Crohn's disease (CD) is a serious, long-lasting inflammation of the digestive system that is becoming more common in Latin America, severely affecting patients' quality of life.
- - A study at a major hospital in Lima, Peru, analyzed 55 CD patients, revealing that the average age of diagnosis was about 56 years, with common symptoms including abdominal pain and weight loss.
- - Key findings included a mix of disease locations and types, predominantly treated with corticosteroids and anti-TNF therapies; about one-third of patients required surgery, and there was a 5.4% mortality rate in the cohort.