Publications by authors named "Jorge Luis Alvarado-Socarras"

Objective: COVID-19 infection may produce severe pneumonia, mainly in the adult population. Pregnant women with severe pneumonia are at high risk of developing complications, and conventional therapy sometimes fails to reverse hypoxemia. Therefore, extracorporeal membrane oxygenation (ECMO) is an option in cases with refractory hypoxemic respiratory failure.

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Background: Adequate oxygenation is essential for sick newborns. Each disease determines the target of oxygenation. Nevertheless, hyperoxia and hypoxia are related to adverse outcomes.

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Background: Therapy with inhaled nitric oxide (iNO) is effective in the management of pulmonary hypertension and severe hypoxemia. However, these benefits have not been demonstrated in preterm infants (<34 weeks). The objective of this report is to present the experience of eight cases of preterm neonates with respiratory distress syndrome (RDS) and refractory hypoxemia, with oligohydramnios history.

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Unlabelled: Adequate pupil dilation is needed to evaluate some neonates at risk of developing illness during this stage. However, this procedure is not free of adverse effects, either local or systemic. One of these complications is the local vasoconstriction of the preterm baby’s skin following the application of mydriatic eye drops.

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Unlabelled: Spontaneous extrahepatic bile duct perforation is rare in newborns. It is a surgical cause of jaundice in this period and the acute presentation is unusual.

Objective: To report a case of spontaneous bile duct perforation in a newborn due to its serious complications if an early and timely diagnosis is not performed.

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Objective: To evaluate the differences in hospital survival between modes of transport to a tertiary center in Colombia for critically ill neonates.

Methods: Observational study of seriously ill neonates transported via air or ground, who required medical care at a center providing highly complex services. Data on sociodemographic, clinical, the Transport Risk Index of Physiologic Stability (TRIPS), and mode of transport were collected.

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We report a male infant with midline defects, congenital heart disease and polydactyly, features suggestive of trisomy 13. However, the report of the karyotype was normal. By clinical findings the final diagnosis was likely to be Pseudotrisomy 13.

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Article Synopsis
  • Extracorporeal membrane oxygenation (ECMO) is a critical life-support therapy for neonates with severe cardiorespiratory issues, particularly useful when conditions are reversible in babies over 34 weeks old.
  • Selecting appropriate patients for ECMO and using it promptly is crucial for successful outcomes, despite newer treatments reducing its general use for hypoxemic respiratory failure.
  • This report highlights the initial cases of neonates with hypoxemic respiratory failure treated with ECMO at Fundación Cardiovascular de Colombia, illustrating a growing experience in managing complex cases like congenital diaphragmatic hernia.
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