Publications by authors named "Jorge Lopez de Leon"
Article Synopsis
- Intraspecific variation in snake venoms is notable, yet there are limited studies in Mexico, particularly involving the medically significant Crotalus basiliscus rattlesnake.
- Research reveals that juvenile rattlesnake venoms are more lethal and contain higher levels of certain toxins compared to adult venoms, which show a distinct biochemical profile.
- The study highlights the efficacy of different lots of Birmex antivenom, noting their ability to neutralize some venom but not crotamine, suggesting the need for better incorporation of this toxin in antivenom production for improved effectiveness.
Article Synopsis
- The genus Metlapilcoatlus in Mexico includes four snake species, and this study is the first to analyze their venom composition.
- Venom analysis showed significant differences between neonates and adults, with neonates having a high content of certain proteases but lacking others, while adults possess different proteins and exhibit procoagulant activities.
- Alarmingly, both neonate and adult venoms were not neutralized by two Mexican therapeutic antivenoms, raising concerns about treatment options for bites from these snakes.
