Polycyclic Aromatic Hydrocarbons in Antarctic Ice Core: Prior Study by Homogeneous Liquid-Liquid Extraction and High-Performance Liquid Chromatography.

Organic contamination has been less investigated in Antarctic snow and ice than in other matrices due to analytical operational problems. In this study, the concentration of 14 Polycyclic Aromatic Hydrocarbons was determined in a shallow firn core by Homogeneous Liquid-Liquid Extraction and High-Performance Liquid Chromatography with a Fluorescence Detector. This investigation aimed to develop a simple analytical methodology for future application directly in fieldwork, taking advantage of the simplicity and small sample volumes.

Production of cell-penetrating peptides in Escherichia coli using an intein-mediated system.

Cell-penetrating peptides are molecules with the ability to cross membranes and enter cells. Attention has been put on these peptides as a tool for drug delivery research, as they are able to serve as delivery vectors for large molecules. Intracellular delivery of bioactive peptides is a very promising research area for clinical applications, since peptides are able to simulate protein regions and thus modulate key intracellular protein-protein interactions.