Publications by authors named "Jorge Ivan Estrada Acevedo"
Background: In recent years, the life expectancy of HIV patients has increased due to the introduction and development of antiretroviral therapies. However, although it has become a chronic pathology, the patients present a higher metabolic, hepatic, and renal risk and a greater aging than the general population.
Objective: To identify the main factors associated with clinical alterations in patients with HIV.
Objective: To identify sociodemographic, clinical, and pharmacological factors associated with nonadherence to antiretroviral treatment in patients with human immunodeficiency virus/acquired immunodeficiency syndrome treated between 2017 and 2020 in four cities in Colombia.
Method: An observational, cross-sectional, retrospective study was conducted of a population of patients with human immunodeficiency virus/acquired immunodeficiency syndrome treated between 2017 and 2020. The Morisky-Green scale, the simplified medication adherence questionnaire, and the simplified scale to detect adherence problems to antiretroviral treatment were applied to determine patient adherence.
Article Synopsis
- The study aimed to identify factors linked to virologic failure in HIV patients on antiretroviral treatment in a Colombian health institution from 2007 to 2020.
- It involved analyzing sociodemographic, pharmacological, and clinical data from 5,406 patients, finding a 16.7% rate of virologic failure.
- Key factors associated with virologic failure included treatment duration over one year, low medication possession and adherence ratios, poor CD4 counts, and high cholesterol levels.
Therapeutic failure in moderate and severe psoriasis patients in a health institution - a transversal study of prevalence and demographic determinants.
J Dermatolog Treat
September 2022
Article Synopsis
- - Psoriasis is a chronic condition that greatly affects quality of life, influenced by genetic and environmental factors, with no known cure but various treatment options available that often fail to control symptoms effectively.
- - A study evaluated 1,051 patients with moderate to severe psoriasis to determine factors linked to treatment failure, discovering associations with gender, type of therapy, age, treatment duration, and health-related quality of life.
- - Results indicate that males and those on biologic therapies are more likely to experience treatment failure, while older age and longer treatment duration reduce the likelihood of failure; additionally, higher DLQI scores correlate with increased risk of treatment failure.
Context: currently is recognized the achieving challenge a adequate adherence. There are multiple methods to detect whether a patient is non-adherent, including claims history of drugs in pharmacy. This method has been considered adequate.
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