Publications by authors named "Jorge Isaac Velasco-Santos"
Background: Neuromyelitis optica (NMO or Devic's syndrome), characterized by acute attacks of optic neuritis and transverse myelitis, is associated with antiaquaporin 4 antibodies (anti-NMO-IgG) and it has a higher prevalence in non-Caucasian populations, where multiple sclerosis is less common.
Clinical Case: 41-year-old man, with no significant personal medical history, presented with clinical symptoms including paresthesias in the right hemibody and homonymous hemianopsia in the left eye. Three weeks later, he developed lumbalgia associated with paresthesias in both lower limbs up to the T7 sensory level, as well as acute urinary retention, followed by paraplegia.
Article Synopsis
- COVID-19 has led to a significant health crisis, emphasizing the need for risk assessment at hospitalization to identify high-risk patients with potential complications.
- Dysnatremia, particularly hypernatremia, has emerged as a key predictor of mortality in COVID-19 patients, with this study aiming to assess its impact on 28-day mortality and related hospital outcomes.
- The study analyzed 722 COVID-19 patients, finding that hypernatremia correlated with increased mortality rates, higher risks for acute kidney injury (AKI), and greater needs for invasive mechanical ventilation (IMV) during hospital stays.
Article Synopsis
- Hyperchloremia, an imbalance of chloride levels in the body, may increase morbidity and mortality, particularly in critically ill patients, and this study explores its link to COVID-19 outcomes.
- The study aimed to see if a sodium-chloride difference of less than 31 mEq/L within 24-48 hours of COVID-19 admission predicts 28-day mortality and other complications like the need for mechanical ventilation and kidney issues.
- Results indicated that while a sodium-chloride difference below 31 mEq/L doesn't predict higher death or ventilation rates, it is linked to a greater risk of acute kidney injury and longer hospital stays for COVID-19 patients.