[Reproducibility and sensitivity of the Impact of Weight on Quality of Life questionnaire among obese Mexicans].

Objective: Determine if the Spanish version of the IWQOL (Impact of Weight on Quality of Life) questionnaire is reproducible and sensitive to detect differences among WHO's classification of obesity.

Methods: The IWQOL was translated into Spanish and adapted to the Mexican context while maintaining a wide comprehensive vocabulary applicable to Latin American countries. We measured reproducibility using a test-retest method (n=82, BMI 37.

[Parental influence in children's food preferences. The ESFUERSO study in two primary schools with different socioeconomic gradients].

Objective: Programs aimed at obesity prevention among elementary school age children have failed. In the present study, we analyzed the association between parental and child food preferences and determined whether this is influenced by the parents' gender and socio-economic status.

Material And Methods: We invited 300 children from a state elementary school (SES) and368 from a private middle class school (PMCS) to participate.

Influence of skin color on the diagnostic utility of clinical acanthosis nigricans to predict insulin resistance in obese patients.

Background: Skin color may influence the presence of acanthosis nigricans (AN) as predictor of insulin resistance (IR). The objective of this study was to determine how skin color influences the diagnostic utility of AN as a marker of IR.

Methods: We designed a cross-sectional study.

[Relationship between morphological diagnosis of NASH (non-alcoholic steatohepatitis) and liver function tests in a group of patients with morbid obesity].

Unlabelled: The non-alcoholic steato-hepatitis (NASH) is a common disorder in obese, type 2 diabetics, female and patients with dislipidaemia. Hepatic biochemical test are abnormal. Despite the lack of its own morphological characteristics, NASH can be differentiated from other pathologies, the gold standard for diagnosis is liver biopsy.

Impact of surgically-induced weight loss on respiratory function: a prospective analysis.

Background: Morbid obesity (MO) causes several degrees of respiratory impairment that may resolve after weight reduction. The aims of the present study were to investigate the frequency of respiratory impairment in a selected cohort of morbidly obese patients with BMI 40-50 kg/m(2) with no respiratory symptoms and to evaluate the impact of surgically-induced weight loss on respiratory function.

Methods: Prospective analysis of respiratory impairment was conducted before surgery and 1 year after surgery in a cohort of patients with MO who underwent vertical banded gastroplasty (VBG).

Early malnutrition and metabolic abnormalities later in life.

Early malnutrition has been significantly associated with chronic diseases later in life. The finding of metabolic abnormalities in individuals with malnutrition in fetal life and early in postnatal life may have important public health implications in developing countries, although only a few studies have examined the relationship between body weight at the first year of life and later metabolic abnormalities. We assessed the effects of malnutrition during the first year of life (independent of birth weight) on several metabolic parameters in young men.

Family-based association study between the monoamine oxidase A gene and obesity: implications for psychopharmacogenetic studies.

Family studies have reported that obesity has a strong heritable component. It has been suggested that a neurotransmitter dysfunction could be involved in mental disorders and obesity; therefore, candidate genes in psychiatric disorders could be a risk factor for obesity. We investigated the association between the monoamine oxidase A (MAO-A) gene and obesity.

Laparoscopic Roux-en-Y gastric bypass for morbid obesity: results of our learning curve in 100 consecutive patients.

Background: Morbid obesity requires life-long treatment, and bariatric surgery provides the best results. Among the bariatric procedures, laparoscopic Roux-en-Y gastric bypass (LRYGBP) has been considered to be superior. However, it requires advanced laparoscopic skills and a learning curve.

Reliability and accuracy of a cardiovascular risk questionnaire and body shape figures for body size in Mexican obese subjects.

Unlabelled: There is little information about the validity of questionnaires used by research related to obesity. The aim of this study was to demonstrate the reliability and accuracy of a cardiovascular risk questionnaire and perception of body size pictorials (BSP) measured in Mexican obese subjects. This was a cross-sectional study designed as two independent phases.

[Prevalence of psychiatric disorders in patients with severe obesity waiting for bariatric surgery].

Introduction: Obesity is a chronic condition, in which different systems of the body are affected. There are some previous studies in which the prevalence of psychiatric disorders in extreme obese patients has been reported, but there are some methodological problems. As far as we know this is the first report of the prevalence of psychiatric disorders in obese patients that need to have a surgical treatment for this disorder in Mexico.

Abnormal SPECT myocardial perfusion imaging during periods of obstructive sleep apnea in morbid obese patients without known heart disease.

Objective: Determine the myocardial perfusion characteristics in obstructive sleep apnea and its possible role in cardiovascular damage.

Methods And Procedures: Fourteen patients from the Obesity Clinic weighing less than 130 kg underwent myocardial perfusion studies using single photon emission computed tomography with technetium 99m-labeled sestamibi during nighttime polysomnographic recordings. Coronary angiograms were performed on patients with suspect of severe coronary obstruction according nighttime myocardial perfusion studies or pharmacological stress carried out during waking hours.

Short stature is related to high body fat composition despite body mass index in a Mexican population.

Background: Mexico has a high prevalence of short stature (SS) population; thus, body mass index (BMI) criteria for diagnosis of obesity should be different from that in a tall stature (TS) population. The aim of this study was to determine whether SS at the same BMI would have greater body fat mass than those with TS.

Methods: We studied 116 individuals, 58 with SS (women < or =1.

Menstrual cycle length disorders in 18- to 40-y-old obese women.

Objective: The objective of this study was to measure the relation between menstrual cycle length disorders and degree of obesity.

Methods: We enrolled 120 obese patients ages 18 to 40 y from an outpatient obesity clinic in a cross-sectional study. Patients with polycystic ovarian syndrome were excluded.

[Accuracy and diagnostic utility of the Hospital Anxiety and Depression Scale (HAD) in a sample of obese Mexican patients].

The Hospital Anxiety and Depression Scale (HAD) have been used in Mexico in drug abusers, burned patients, older people, with renal insufficiency and high-risk pregnant women. The aim of this study was to determine reproducibility and accuracy of the questionnaire in a sample of obese subjects. A group of 75 obese patients (BMI > 27) without diabetes mellitus were invited to participated in the study.

Open versus laparoscopic vertical banded gastroplasty: a randomized controlled double blind trial.

Background: Vertical banded gastroplasty (VBG) is a frequently used surgical procedure for the treatment of morbid obesity. It can be done open (OVBG) or laparoscopic (LVBG). The aim of this double-blind randomized clinical trial was to compare the postoperative outcome and 1-year follow-up of 2 cohorts of patients who underwent either OVBG or LVBG.

Poorly controlled type I diabetes mellitus in young men selectively suppresses luteinizing hormone secretory burst mass.

Alterations in the reproductive axis function are present to a variable extent in patients with type 1 diabetes mellitus (IDDM). Results from studies in IDDM men have yielded discrepant findings, which may reflect nonuniform patient selection criteria, age, diabetic status, duration of the disease and differences in sampling protocols. To more clearly define the impact of early diabetic alterations in the male reproductive axis, we applied a combined strategy of patient selection restricted to young men with relatively short duration of IDDM, dual control groups, multiparameter deconvolution analysis to assess LH secretory activity, and assessment of time-dependent changes in human chorionic gonadotropin (hCG)-stimulated serum testosterone concentrations.

Quality of life in bariatric surgery.

Background: Bariatric surgery is the treatment of choice for morbid obesity. Since bariatric operations alter gastrointestinal anatomy, they may induce symptoms that have a negative impact on quality of life (QOL). The aim of this study was to prospectively analyze QOL after bariatric surgery.

Nortriptyline and fluphenazine in the symptomatic treatment of diabetic neuropathy. A double-blind cross-over study.

A controlled clinical trial on the efficacy of a nortriptyline-fluphenazine combination was carried out in patients with painful diabetic polyneuropathy. A visual analog scale was used to evaluate the relief of pain or paresthesia. Significant relief of both pain and paresthesia was obtained with this combination.