Abdominal wall hernias in end-stage renal disease patients on peritoneal dialysis.

Objective: To describe our experience with hernioplasty in peritoneal dialysis patients and to identify possible risk factors for surgical complications.

Design: A 4-year retrospective chart review of data.

Setting: Peritoneal dialysis unit of a university hospital.

Pediatric renal transplantation with mycophenolate mofetil immunosuppression in a single center from Mexico.

An MMF-based immunosuppression has reduced the acute rejection rate in adults and in children in the early post-transplantation period. In the present study, pediatric renal transplantation patients on a CyA, MMF, and steroids regimen were prospectively evaluated. Patients with CyA, MMF, and steroid therapy without antibody induction were evaluated for surgical aspects, renal function, rejection, and survival, growth after transplantation, adverse events and medication discontinuation.

Living related kidney transplantation without calcineurin inhibitors: initial experience in a Mexican center.

We performed a prospective randomized trial comparing sirolimus/mycophenolate mofetil (MMF)/prednisone to cyclosporine/MMF/prednisone and selected induction therapy with basiliximab. Twenty patients received sirolimus (10 mg loading dose followed by 3 mg/m body surface area/day, keeping 24-hr trough levels at 10-15 ng/mL for six months and 5-10 ng/mL thereafter. Twenty-one patients began cyclosporine (4 to 8 mg/kg/day, keeping 12-hour trough levels at 150-300 ng/mL for 6 months and 100-200 ng/mL afterwards).

[Blunt trauma in kidney transplant with preservation of renal function].

A 35-year-old male received a living related kidney transplant. At 184 months posttransplantation he suffered a direct right iliac fossa blunt trauma while working on a machine in a steel factory. Graft pain, dysuria and gross hematuria were observed and CT showed a periallograft hematoma.

Conversion from calcineurin inhibitor to sirolimus for renal function deterioration in kidney allograft recipients.

Background: Calcineurin inhibitors play an important role in chronic allograft dysfunction. Sirolimus is an interesting alternative in renal transplant patients because it is less nephrotoxic than calcineurin inhibitors.

Methods: A chart review of the clinical outcome of kidney transplant patients converted to sirolimus with progressive allograft dysfunction is reported herein.