Publications by authors named "Jorge Eduardo Angeles"

Background: Magnetic resonance elastography (MRE) can determine the presence and stage of liver fibrosis. Data on normative MRE values, while reported in adults, are limited in children.

Purpose: To determine the distribution of MRE-measured liver stiffness in children without liver disease.

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Article Synopsis
  • Magnetic resonance elastography (MRE) is an effective noninvasive technique for assessing liver fibrosis in children with nonalcoholic fatty liver disease (NAFLD), though research in this area is still limited.
  • A multicenter study analyzed 2D MRE readings from 90 children, resulting in strong correlations between manual and automated analyses for detecting fibrosis stages.
  • The study found that MRE had a cross-validated accuracy of 72.2% for any fibrosis and 86.7%-90.0% for advanced fibrosis, suggesting that further refinement of automated techniques is needed for wider clinical use.
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