Concomitant loss of heterozygosity at the BRCA1 and FHIT genes as a prognostic factor in sporadic breast cancer.

Previous studies have shown loss of heterozygosity (LOH) at the BRCA1 and FHIT genes in sporadic primary breast cancer. The aim of this study was to evaluate concomitant LOH at the BRCA1 and FHIT genes in sporadic breast cancer and investigate its influence on patient survival. Loss of heterozygosity was determined using microsatellite markers.

[Hepatitis C recurrence after living donor and cadaveric liver transplantation].

Objective: To determine the recurrence of hepatitis C in patients subjected to living donor liver transplantation compared to those subjected to cadaveric liver transplantation.

Methods: Of a total of 333 liver transplantations, 279 (83.8%) were cadaveric liver transplantation and 54 (16.

[Comparison of pre-operative exams and per-operative findings in living donor liver transplantation].

Background: Success in living donor liver transplantation is associated to donor vascular and biliar anatomy.

Aim: Compare pre-operative and per-operative findings in living liver donors related to portal vein, hepatic artery, bile duct and hepatic venous drainage anatomy.

Methods: Donors charts of living donor liver transplants done at Clinics Hospital of the Federal University of Paraná, Curitiba, PR, Brazil, were reviewed between March 1998 and August 2005.

Successful twin pregnancy after orthotopic liver transplantation.

Aim: Report of a case of successful twin pregnancy following liver transplantation.

Patient And Method: A 42-year-old nulliparous-woman was subjected to an orthotopic liver transplantation due to Budd-Chiari syndrome. Sixteen months after the transplantation, an ultrasonography revealed twin pregnancy.