Fatal attraction: intestinal amebiasis and COVID-19 as risk factors for colonic perforation.

The parasite , the causal agent of amebiasis, is considered a worldwide emergent disease and still represents an important cause of death in Mexico. Here, we describe a clinical case, involving an inflammatory response to both Coronavirus Infectious Disease 2019 (COVID-19) and intestinal amebiasis 54-year-old, COVID-positive Mexican gentleman was admitted to surgery following 6 days of hematochezia. An exploratory laparotomy and colonoscopy revealed multiple fibrous and amebic ulcerations (5-10 cm in diameter), with necrotic tissue predominantly localized in the sigmoid, descending and ascending colon.

Expression of a novel surfactant protein gene is associated with sites of extrapulmonary respiration in a lungless salamander.

Numerous physiological and morphological adaptations were achieved during the transition to lungless respiration that accompanied evolutionary lung loss in plethodontid salamanders, including those that enable efficient gas exchange across extrapulmonary tissue. However, the molecular basis of these adaptations is unknown. Here, we show that lungless salamanders express in the larval integument and the adult buccopharynx-principal sites of respiratory gas exchange in these species-a novel paralogue of the gene (), which is a critical component of pulmonary surfactant expressed exclusively in the lung in other vertebrates.

Growth Factor Independence-1 () Is Required for Pancreatic Acinar Unit Formation and Centroacinar Cell Differentiation.

Background & Aims: The genetic specification of the compartmentalized pancreatic acinar/centroacinar unit is poorly understood. Growth factor independence-1 () is a zinc finger transcriptional repressor that regulates hematopoietic stem cell maintenance, pre-T-cell differentiation, formation of granulocytes, inner ear hair cells, and the development of secretory cell types in the intestine. As / is expressed in human and rodent pancreas, we characterized the potential function of in mouse pancreatic development.

[Usefulness of office hysteroscopy].

Objective: To demonstrate the efficacy and feasibility of the office hysteroscopy in the treatment of the endouterine pathologies.

Design: retrospective, descriptive and observational.

Patients And Method: We included all the office hysteroscopies performed since February-2000 to August-2004 (n=84) in a private medical office.