High sensitivity flow cytometry immunophenotyping increases the diagnostic yield of malignant pleural effusions.

Diagnosing malignant pleural effusions (MPE) is challenging when patients lack a history of cancer and cytopathology does not detect malignant cells in pleural effusions (PE). We investigated whether a systematic analysis of PE by flow cytometry immunophenotyping (FCI) had any impact on the diagnostic yield of MPE. Over 7 years, 570 samples from patients with clinical suspicion of MPE were submitted for the FCI study.

Defining the Heterogeneity of Sleep Apnea Syndrome: A Cluster Analysis With Implications for Patient Management.

Introduction: Obstructive sleep apnea (OSA) is a complex pathology with heterogeneity that has not been fully characterized to date. Our objective is to identify groups of patients with common clinical characteristics through cluster analysis that could predict patient prognosis, the impact of comorbidities and/or the response to a common treatment.

Methods: Cluster analysis was performed using the hierarchical cluster method in 2025 patients in the apnea-HUGU cohort.

Findings and Prognostic Value of Lung Ultrasound in COVID-19 Pneumonia.

Objectives: The aim of this study was to systematically describe the findings of lung ultrasound (US) in patients with coronavirus 2019 (COVID-19) pneumonia and to analyze its prognostic value.

Methods: Lung US examinations were performed in 63 patients with COVID-19 pneumonia admitted to a university hospital. Lung involvement was evaluated on a 4-point scale with a 12-area pulmonary division, obtaining a lung score (LS).