[Pharmacological Treatment of Apathy in Parkinson's Disease: a Systematic Review of the Literature].

Introduction And Objectives: Apathy, defined as a deficit for initiating and maintaining action, is a symptom affecting patients with diverse psychiatric and neuropsychiatric diseases, including dementia, sequelae of traumatic brain injury, schizophrenia, depression, and Parkinson's disease (PD). Apathy negatively affects function and quality of life of PD patients, and it is an important cause of caregiver's distress. The pharmacological treatment of apathy in PD is the focus of this systematic review.

"When I Want to Cry I Can't": Inability to Cry Following SSRI Treatment.

Introduction: We describe seven cases of patients with an inability to cry after treatment with selective serotonin re-uptake inhibitor (SSRI) medication, even during sad or distressing situations that would have normally initiated a crying episode, in the light of the role of the serotonergic system in emotional expression.

Method: Case series drawn from patients attended in a secondary care psychiatry service.

Results: While excessive crying without emotional distress has been previously reported in the literature, and is associated with reduced serotonin function, these reports suggest cases of the reverse dissociation, where emotional distress and an urge to cry was present, but crying was impaired.

[Autonomy, Trust and Medical Ethics in Onora O'Neill's Work].

Introduction: Autonomy has become a key concept in bioethics. Onora O'neill is perhaps the most representative author and researcher in the philosophical and bioethical fields regrding the concept of autonomy.

Object: To review the concept of autonomy in Onora O'Neill's work so as to understand its relevance in current bioethics.