Publications by authors named "Jorge Balaguer-German"

Heart failure (HF) is a highly prevalent syndrome in elderly subjects. Currently, multiple drugs have shown clinical benefits in patients with HF and reduced ejection fraction (HFrEF). However, evidence is scarce in elderly patients (beyond 75 years old), even more so for the latest drugs, such as angiotensin receptor-neprilysin inhibitors (ARNIs).

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(1) Background: The validation of new lines of therapy for the elderly is required due to the progressive ageing of the world population and scarce evidence in elderly patients with HF with reduced ejection fraction (HFrEF). The purpose of our study is to analyze the effect of SGLT2 inhibitors (SGLT2i) in this subgroup of patients. (2) Methods: A single-center, real-world observational study was performed.

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Aims: Heart failure (HF) with reduced left ventricle ejection fraction (LVEF) is an entity with poor prognosis characterized by decompensations. Bioelectrical impedance analysis (BIA) is used to assess volume overload (VO) and may be useful to identify apparently stable HF outpatients at risk of decompensation. The aim of this study is to analyse whether VO assessed by BIA is associated with worsening heart failure (WHF) in stable outpatients with HF and reduced LVEF (HFrEF).

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Article Synopsis
  • ATTR amyloidosis is a key cause of heart failure, and research aimed to find connections between cardiac function (measured by global longitudinal strain or GLS), biomarkers, and patient performance.
  • In a study involving 13 patients, various echocardiographic assessments, including GLS and a 6-minute walk test, were conducted alongside measuring inflammatory and cardiovascular biomarker levels.
  • Results showed significant correlations between GLS and NT-ProBNP, indicating better prognosis with more negative strain values, and that Klotho levels were linked to overall clinical performance in patients with ATTR amyloidosis.
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Aims: Residual congestion at the time of hospital discharge is an important readmission risk factor, and its detection with physical examination and usual diagnostic techniques have strong limitations in overweight and obese patients. New tools like bioelectrical impedance analysis (BIA) could help to determine when euvolaemia is reached. The aim of this study was to investigate the usefulness of BIA in management of heart failure (HF) in overweight and obese patients.

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