Searching Hit Potential Antimicrobials in Natural Compounds Space against Biofilm Formation.

Biofilms are communities of microorganisms that can colonize biotic and abiotic surfaces and thus play a significant role in the persistence of bacterial infection and resistance to antimicrobial. About 65% and 80% of microbial and chronic infections are associated with biofilm formation, respectively. The increase in infections by multi-resistant bacteria instigates the need for the discovery of novel natural-based drugs that act as inhibitory molecules.

Interaction with Soil Bacteria Affects the Growth and Amino Acid Content of .

Exploration of the effect of soil bacteria on growth and metabolism of beneficial root endophytic fungi is relevant to promote favorable associations between microorganisms of the plant rhizosphere. Hence, the interaction between the plant-growth-promoting fungus and different soil bacteria was investigated. The parameters studied were fungal growth and its amino acid composition during the interaction.