Complete genome and transcriptome of 3488, a clinical isolate with a novel deletion at the RD1 locus.

In members of the complex, the RD1 locus encodes a type VII secretion system involved in virulence. Herein, we describe the genome and transcriptomic analysis of 3488, a clinical isolate from a cat, with a 14.2 kb deletion that encompasses the RD1 locus.

Whole-Genome sequencing in routine epidemiology - scoping the potential.

the main agent of bovine tuberculosis (bTB), presents as a series of spatially-localised micro-epidemics across landscapes. Classical molecular typing methods applied to these micro-epidemics, based on genotyping a few variable loci, have significantly improved our understanding of potential epidemiological links between outbreaks. However, they have limited utility owing to low resolution.