Publications by authors named "Jordi Puiguriguer"

Article Synopsis
  • This study evaluates the clinical features and outcomes of acute cannabis toxicity versus acute synthetic cannabinoid receptor agonist toxicity in European emergency departments from 2013-2020.
  • Using data from the European Drug Emergencies Network Plus, researchers analyzed 2,657 cases of cannabis exposure and 503 cases of synthetic cannabinoid exposure to compare their effects.
  • The findings indicate that synthetic cannabinoid exposures are linked to more severe neuropsychiatric symptoms, while cannabis exposures are associated with cardiovascular issues.
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Background: Digoxin poisonings are relatively common and potentially fatal, requiring immediate therapeutic intervention, with special attention to the patient's hemodynamic status and the presence of electrocardiographic and electrolytic disturbances.

Objective: To identify factors associated with seven-day and thirty-day mortality in digoxin poisoning.

Design, Settings And Participants: A retrospective, observational, multicenter study was conducted across 15 Hospital Emergency Departments (HED) in Spain.

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Objectives: Digoxin toxicity accounts for a small percentage of poisonings attended by emergency departments. This study aimed to describe differences between acute and chronic digoxin toxicity and assess the use of digoxin-specific antibody fragments (digoxin-Fab) as an antidote.

Material And Methods: Retrospective, observational, multicenter study in 15 hospital emergency departments in 8 Spanish autonomous communities in 7 years.

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In order to identify the sociodemographic, clinical, emergency management and severity differences of drug poisoning treated in Emergency Departments (ED) from a gender perspective, data on patients from 11 Spanish EDs were recorded over 24 months (August 2017-July 2019). The severity of intoxication was compared by sex and was based on the combined adverse event (orotracheal intubation, cardiorespiratory arrest, intensive care hospitalization, and death). We included 4,526 patients (men 75.

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Methoxetamine (MXE) and the arylcyclohexylamines 3-methoxy-PCP (3-MeO-PCP) and 4-methoxy-PCP (4-MeO-PCP) are substituted analogs of the dissociative psychoactive substances ketamine and phencyclidine (PCP), respectively. They have emerged on the new psychoactive substances (NPS) market as legal alternatives to these classically banned dissociatives. Little data has been published regarding the cross-reactivity of these NPS in PCP immunoassays (IAs).

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Objectives: To analyze epidemiologic, clinical, and care characteristics in cases in which patients came to 2 Spanish emergency departments (EDs) with symptoms caused by recreational drug abuse. To compare the characteristics with those reported for other areas of Europe.

Material And Methods: Secondary analysis of the registry of the European Drug Emergencies Network (Euro-DEN Plus), which collects cases in 14 European countries and 20 EDs.

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Article Synopsis
  • The study aimed to analyze the clinical profile of GHB (gamma-hydroxybutyrate) and GBL (gammabutyrolactone) intoxication among European patients, focusing on differences between those using these substances alone versus in combination with other drugs.
  • Data were collected over 12 months from Emergency Departments in the Euro-DEN network, including 710 intoxication cases, mostly affecting young males (mean age 31).
  • Key findings revealed that most patients arrived by ambulance during weekends, often combining GHB/GBL with other substances like alcohol and amphetamines, leading to a higher incidence of severe symptoms and longer hospital stays compared to those using GHB/GBL alone.
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Introduction And Objectives: Emergency departments (EDs) in Spanish hospitals daily attend a large number of patients for adverse reactions or clinical complications resulting from cocaine use. After discharge, some of these patients revisit the ED for the same reason within a year. The objective of the present study was to quantify the rate of such revisits and identify the factors associated with them.

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We present a map of 24 indicators to measure the quality of care given to patients with acute poisoning attended in the emergency department. These include structural indicators (availability of protocols, stocks of antidotes, analytical tests, gastric lavage tubes), process indicators (correct indication of gut decontamination techniques, indications for renal and extra-renal purification, use of antidotes, indication of toxicological analyses, ECG, delays in care, psychiatric referrals, judicial notifications), indicators of results (mortality, compliance with minimum basic data set of poisonings, continuing staff education) and administrative indicators (publications).

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