Publications by authors named "Jordana Mashiach"

Article Synopsis
  • * The study included 346 patients resulting in 496 IVF cycles, revealing no significant difference in pregnancy, live birth, or miscarriage rates between day 3 and day 5 embryo transfers, despite higher cancellation rates for day 5 transfers.
  • * Conclusions suggest that while day 5 culture can lead to more cancellations due to failed blastocyst formation, it does not negatively impact pregnancy outcomes and may streamline the IVF process for older women.
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Purpose: This survey study aims to examine the quality of planned oocyte cryopreservation (POC) decision-making in the domains of decision change, decision difficulty, decision regret and informed choice.

Methods: Of the 224 women who completed at least one POC cycle between 2012 and 2018 at a Canadian academic IVF centre, 198 were reachable by email for anonymous survey participation.

Results: Ninety-eight questionnaires were returned (response rate 49.

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Objective: To study whether intratesticular (IT) administration of 2 sources of human umbilical cord perivascular cells (HUCPVC), rich and potent sources of mesenchymal stromal cells (MSC), before chemotherapy can prevent infertility in a mouse model.

Design: Two control groups of CD1 male mice without busulfan (BUS) administration (untreated and IT media injection groups) were included. Experimental groups included IT administration of media, first trimester (FTM) HUCPVCs or term HUCPVCs (n = 5 each) injected 3 days before BUS treatment (20 mg/kg).

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Background: Delayed parenthood, by both women and men, has become more common in developed countries. The adverse effect of advanced maternal age on embryo aneuploidy and reproductive outcomes is well known. However, whether there is an association between paternal age (PA) and embryonic chromosomal aberrations remains controversial.

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Article Synopsis
  • The study aimed to explore the relationship between paternal age and chromosomal abnormalities in embryos, using data from embryos created with young egg donors and genetic testing for chromosome issues.
  • A total of 3,118 embryos from 407 male patients were analyzed, divided into three groups based on paternal age: ≤39, 40-49, and ≥50 years.
  • Results showed no significant differences in embryo genetic outcomes among the different age groups, but fertilization rates were lower for older fathers, with a consistent blastocyst formation rate across all groups.
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