Publications by authors named "Jordan Rull"
J Clin Oncol
October 2024
Article Synopsis
- Mucinous neoplasms of the gastrointestinal tract, particularly from the appendix, are known to spread to the peritoneum, resulting in poor treatment outcomes and low response rates to traditional chemotherapy, prompting research into alternative therapies.*
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- A study involving 16 patients with peritoneal mucinous carcinomatosis examined the efficacy of palbociclib, a CDK4/6 inhibitor, which showed a significant decrease in tumor markers and stable disease in 50% of patients after 12 months.*
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- The findings suggest that palbociclib may offer a better clinical response for patients with mutations in the targeted oncogene compared to conventional cytotoxic treatments, indicating potential for further research in this area
