Pyoderma gangrenosum post open radical prostatectomy - A complication every urologist should consider and recognise.

Post-operative pyoderma gangrenosum is a rare neutrophilic dermatosis which forms within skin wounds following surgery. This condition is not well recognised, can be difficult to diagnose and often mimics necrotising fasciitis. While wound exploration and debridement remains the standard of care in post-operative wound infection, this can paradoxically exacerbate pyoderma gangrenosum resulting in further morbidity and mortality.

An unusual complication of bacterial prostatitis.

Acute bacterial prostatitis is a common genitourinary infection affecting males. () is a leading uropathogen implicated in cases of acute bacterial prostatitis, but is not attributed as a common cause of acute myocarditis. This article reports on an unusual case of concurrent myocarditis in a young man with -related prostatitis and urinary sepsis.

Intralesional steroid injection combined with bladder neck incision is efficacious in the treatment of recurrent bladder neck contracture.

Objectives: Bladder neck contracture (BNC) is a well-recognized complication following radical prostatectomy (RP). This problem may recur after failing initial endoscopic management. This study evaluated the efficacy of intralesional steroid injection combined with bladder neck incision (BNI) for recurrent BNC following RP.

Splenogonadal fusion: A case of two lesions.

Splenogonadal fusion is a rare congenital anomaly that presents as a testicular mass and is clinically difficult to distinguish from primary malignancy. It is a benign condition which commonly results in a radical orchidectomy. This case report describes a 22-year-old male with a new multi-focal lesion discovered on self-examination.

Implementing a Clinical Practice Change: Adopting the Nutrition Care Process.

The Nutrition Care Process (NCP), created by the Academy of Nutrition and Dietetics, provides a framework that encourages critical thinking and promotes uniform documentation by Registered Dietitians (RD). Additionally, it creates a link between the nutrition assessment, nutrition intervention, and the predicted or actual nutrition outcome. NCP has been integrated into a number of institutions in Canada and internationally.

Loss of CDH1 and Pten accelerates cellular invasiveness and angiogenesis in the mouse uterus.

E-cadherin (CDH1) is a cell adhesion molecule that coordinates key morphogenetic processes regulating cell growth, cell proliferation, and apoptosis. Loss of CDH1 is a trademark of the cellular event epithelial to mesenchymal transition, which increases the metastatic potential of malignant cells. PTEN is a tumor-suppressor gene commonly mutated in many human cancers, including endometrial cancer.

CDH1 is essential for endometrial differentiation, gland development, and adult function in the mouse uterus.

CDH1 is a cell-cell adhesion molecule expressed in the epithelium to coordinate key morphogenetic processes, establish cell polarity, and regulate epithelial differentiation and proliferation. To determine the role of CDH1 in the mouse uterus, Cdh1 was conditionally ablated by crossing Pgr-Cre and Cdh1-flox mice, and the phenotype was characterized. We found that loss of Cdh1 results in a disorganized cellular structure of the epithelium and ablation of endometrial glands in the neonatal uterus.

Periareolar injection for localization of sentinel nodes in breast cancer patients.

The goal of this study was to evaluate the periareolar injection of technetium 99m sulfur colloid to identify axillary sentinel nodes and compare the number of sentinel lymph nodes identified with preoperative lymphoscintigraphy to intraoperative biopsy using a handheld gamma probe. A total of 104 consecutive patients diagnosed with invasive breast cancer participated in this prospective study, with 81 patients receiving an intradermal periareolar injection and 23 patients receiving an intradermal peritumoral injection of filtered technetium 99m sulfur colloid. Preoperative lymphoscintigraphy was performed for sentinel node mapping and localization.