Publications by authors named "Jordan Lindekens"
Article Synopsis
- The study examined the effects of glucagon-like-peptide 1 receptor agonists (GLP1-RA) on heart transplant recipients dealing with diabetes and obesity, as there has been limited research in this area.
- A total of 74 patients were analyzed, with significant improvements in cardiometabolic parameters such as reduced BMI, lower blood sugar levels (HbA1C), and decreased LDL cholesterol after using GLP1-RA for around 383 days.
- Results indicated that GLP1-RA therapy was effective in managing diabetes and weight in these patients, with minimal impact on their immunosuppression medication adjustments.
Surgery and anesthesia induce inflammatory changes in the central nervous system, which ultimately lead to neuronal damage concomitant with an increase in the level of neurodegeneration markers. Despite some experimental data showing prolonged activation of the immune system post-surgery, no study has determined the extent of long-term elevation of neurodegeneration markers. The purpose of this study was to investigate the serum levels of tau protein, ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1), neurofilament light (NF-L), and glial fibrillary acidic protein (GFAP) after elective cardiac surgery with the implementation of cardiopulmonary bypass (CPB).
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