Publications by authors named "Jordan Childs"
Article Synopsis
- Pathogenic mitochondrial DNA (mtDNA) variants are a frequent cause of mitochondrial diseases in adults, and their levels in blood decrease with age due to different metabolic needs among blood cell types.* -
- A study involving cell-sorting and mtDNA sequencing found that T cells show a greater decline in these variants compared to other blood cells, driven by their ability to eliminate mutated mtDNA as they differentiate.* -
- Compared to healthy controls, patients with these mtDNA variants have fewer T cells, highlighting the importance of mitochondrial function for maintaining T cell levels and differentiation status in the blood.*
Background: Recent data on opioid consumption indicate that patients typically require far less than is prescribed. Prisma Health Upstate Hernia Center adopted standardized postoperative prescribing after hernia repair and began tracking patient-reported opioid utilization. The aim of this study is to evaluate patient opioid use after hernia repair in order to guide future prescribing.
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