Clinical Characteristics and Long-term Outcomes of Pediatric Ulcerative Colitis: A Single-Center Experience in Korea.

Background/aims: : Although pediatric ulcerative colitis (UC) has a different phenotype and clinical course than adult UC, its clinical features and outcomes are poorly defined, especially in Asian populations. This study investigated the clinical features and long-term outcomes of pediatric UC in a Korean population.

Methods: We retrospectively analyzed 208 patients aged <18 years diagnosed with UC between 1987 and 2013.

Synthesis of Sodium Cobalt Fluoride/Reduced Graphene Oxide (NaCoF/rGO) Nanocomposites and Investigation of Their Electrochemical Properties as Cathodes for Li-Ion Batteries.

In this study, sodium cobalt fluoride (NaCoF)/reduced graphene oxide (NCF/rGO) nanocomposites were fabricated through a simple one-pot solvothermal process and their electrochemical performance as cathodes for Li-ion batteries (LIBs) was investigated. The NCF nanoclusters (NCs) on the composites (300-500 nm in size) were formed by the assembly of primary nanoparticles (~20 nm), which were then incorporated on the surface of rGO. This morphology provided NCF NCs with a large surface area for efficient ion diffusion and also allowed for close contact with the conductive matrix to promote rapid electron transfer.

A Review of Functional Separators for Lithium Metal Battery Applications.

Lithium metal batteries are considered "rough diamonds" in electrochemical energy storage systems. Li-metal anodes have the versatile advantages of high theoretical capacity, low density, and low reaction potential, making them feasible candidates for next-generation battery applications. However, unsolved problems, such as dendritic growths, high reactivity of Li-metal, low Coulombic efficiency, and safety hazards, still exist and hamper the improvement of cell performance and reliability.

The First Reported Case of Infant Botulism in Korea: Treatable Infantile Neuromuscular Disease.

Botulism is a rare neuromuscular disorder caused by neurotoxins produced by . The diagnosis of infant botulism may be obscured or delayed, as its presentation is similar to that of infantile neuromuscular disorders. We report the first Korean case of infant botulism in an acute progressive floppy infant with poor sucking and a weak cry.

Epidemiological Correlation between Fecal Adenovirus Subgroups and Pediatric Intussusception in Korea.

We investigated the adenoviral etiology and seasonal epidemic trends in intussusception and each adenoviral subgroup. Also we confirmed whether we can use the adenovirus data of Acute Infectious Agents Laboratory Surveillance Report (AIALSR) as an epidemic predictor of intussusception. Patients with intussusception (n = 126), < 5 years old, were enrolled and matched by age and sex with controls suffering acute gastroenteritis without intussusception (n = 106), all recruited at 8 centers.

Systematic functional profiling of transcription factor networks in Cryptococcus neoformans.

Cryptococcus neoformans causes life-threatening meningoencephalitis in humans, but its overall biological and pathogenic regulatory circuits remain elusive, particularly due to the presence of an evolutionarily divergent set of transcription factors (TFs). Here, we report the construction of a high-quality library of 322 signature-tagged gene-deletion strains for 155 putative TF genes previously predicted using the DNA-binding domain TF database, and examine their in vitro and in vivo phenotypic traits under 32 distinct growth conditions. At least one phenotypic trait is exhibited by 145 out of 155 TF mutants (93%) and ∼85% of them (132/155) are functionally characterized for the first time in this study.

A framework for unpacking cognitive benefits of distributed complex visual displays.

What are the advantages and disadvantages of spatially stacked (i.e., when information sources are presented side-by-side) versus distributed (i.

Placement of covered retrievable expandable metallic stents for pediatric tracheobronchial obstruction.

Purpose: To evaluate the safety and clinical effectiveness of placement of covered retrievable expandable metallic stents in seven children with tracheobronchial obstruction.

Materials And Methods: Using bronchoscopic and fluoroscopic guidance, stent placement was performed in seven children (median age, 12 y; range, 2 mo-14 y). The stents were electively removed 6 months after placement or whenever there were symptom-producing complications.