Publications by Joost R J van Neerven

Publications by authors named "Joost R J van Neerven"

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Vectorial secretion of interleukin-8 mediates autocrine signalling in intestinal epithelial cells via apically located CXCR1.

Oriana Rossi Jurgen Karczewski Ellen H Stolte Robert J M Brummer Michiel A van Nieuwenhoven Joost R J van Neerven

BMC Res Notes

October 2013

Background: In the intestinal mucosa, several adaptations of TLR signalling have evolved to avoid chronic inflammatory responses to the presence of commensal microbes. Here we investigated whether polarized monolayers of intestinal epithelial cells might regulate inflammatory responses by secreting IL-8 in a vectorial fashion (i.e.

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