Squeeze-MNet: Precise Skin Cancer Detection Model for Low Computing IoT Devices Using Transfer Learning.

Cancer remains a deadly disease. We developed a lightweight, accurate, general-purpose deep learning algorithm for skin cancer classification. Squeeze-MNet combines a Squeeze algorithm for digital hair removal during preprocessing and a MobileNet deep learning model with predefined weights.

Enhanced Non-Contact Grip Force and Swirl Stability by a Combined Venturi-Vortex Air Head.

A combination of the venturi module and the vortex cup was proposed to solve vortex instability and to enhance grip capacity. Mounting a venturi suction pad inside the vortex cup improved vacuum generation efficiency. When the vortex cup properly maintained the non-contact air gap and generated an equivalent vacuum to achieve a sealing effect around the open gap of the suction pad, the combined head improved grip capacity and stabilized the non-contact environment.

3-month surgical outcomes of Implantable Collamer Lens implantation for myopic regression after laser vision correction surgeries: a retrospective case series.

Background: To investigate the surgical outcomes of implantable collamer lens (ICL) implantation in eyes with residual myopia after primary laser vision correction (LVC) surgeries.

Methods: This study included patients who underwent ICL implantation and had a history of LVC surgery, including photorefractive keratectomy (PRK) or laser-assisted in situ keratomileusis (LASIK). Visual acuity and refractive error were assessed pre and 3-months postoperatively and the efficacy and safety indices calculated accordingly.

Critical Energy Dissipation in a Binary Superfluid Gas by a Moving Magnetic Obstacle.

We study the critical energy dissipation in an atomic superfluid gas with two symmetric spin components by an oscillating magnetic obstacle. Above a certain critical oscillation frequency, spin-wave excitations are generated by the magnetic obstacle, demonstrating the spin superfluid behavior of the system. When the obstacle is strong enough to cause density perturbations via local saturation of spin polarization, half-quantum vortices (HQVs) are created for higher oscillation frequencies, which reveals the characteristic evolution of critical dissipative dynamics from spin-wave emission to HQV shedding.

Clinical outcomes of immediate transepithelial photorefractive keratectomy after suction loss during small-incision lenticule extraction.

Purpose: To investigate the surgical outcomes of immediate transepithelial photorefractive keratectomy (PRK) after suction loss during small-incision lenticule extraction (SMILE) and compare the outcomes with those of uneventful SMILE.

Setting: Eyereum Eye Clinic, Seoul, South Korea.

Design: Retrospective case series.

eIF2A, an initiator tRNA carrier refractory to eIF2α kinases, functions synergistically with eIF5B.

The initiator tRNA (Met-tRNA ) at the P site of the small ribosomal subunit plays an important role in the recognition of an mRNA start codon. In bacteria, the initiator tRNA carrier, IF2, facilitates the positioning of Met-tRNA on the small ribosomal subunit. Eukarya contain the Met-tRNA carrier, eIF2 (unrelated to IF2), whose carrier activity is inhibited under stress conditions by the phosphorylation of its α-subunit by stress-activated eIF2α kinases.

Critical Spin Superflow in a Spinor Bose-Einstein Condensate.

We investigate the critical dynamics of spin superflow in an easy-plane antiferromagnetic spinor Bose-Einstein condensate. Spin-dipole oscillations are induced in a trapped condensate by applying a linear magnetic field gradient and we observe that the damping rate increases rapidly as the field gradient increases above a certain critical value. The onset of dissipation is found to be associated with the generation of dark-bright solitons due to the modulation instability of the counterflow of two spin components.

Observation of vortex-antivortex pairing in decaying 2D turbulence of a superfluid gas.

In a two-dimensional (2D) classical fluid, a large-scale flow structure emerges out of turbulence, which is known as the inverse energy cascade where energy flows from small to large length scales. An interesting question is whether this phenomenon can occur in a superfluid, which is inviscid and irrotational by nature. Atomic Bose-Einstein condensates (BECs) of highly oblate geometry provide an experimental venue for studying 2D superfluid turbulence, but their full investigation has been hindered due to a lack of the circulation sign information of individual quantum vortices in a turbulent sample.

Observation of von Kármán Vortex Street in an Atomic Superfluid Gas.

We report on the experimental observation of vortex cluster shedding from a moving obstacle in an oblate atomic Bose-Einstein condensate. At low obstacle velocities v above a critical value, vortex clusters consisting of two like-sign vortices are generated to form a regular configuration like a von Kármán street, and as v is increased, the shedding pattern becomes irregular with many different kinds of vortex clusters. In particular, we observe that the Stouhal number associated with the shedding frequency exhibits saturation behavior with increasing v.

eIF2A mediates translation of hepatitis C viral mRNA under stress conditions.

Translation of most mRNAs is suppressed under stress conditions. Phosphorylation of the α-subunit of eukaryotic translation initiation factor 2 (eIF2), which delivers initiator tRNA (Met-tRNA(i)) to the P site of the 40S ribosomal subunit, is responsible for such translational suppression. However, translation of hepatitis C viral (HCV) mRNA is refractory to the inhibitory effects of eIF2α phosphorylation, which prevents translation by disrupting formation of the eIF2-GTP-Met-tRNA(i) ternary complex.

Minocycline inhibition of photoreceptor degeneration.

Objective: To determine whether systemic minocycline can protect photoreceptors in experimental retinal detachment (RD).

Methods: Retinal detachment was induced in mice by subretinal injection of sodium hyaluronate, 1.4%.

Modified external needle drainage of subretinal fluid in primary rhegmatogenous retinal detachment: a prospective, consecutive, interventional, single-surgeon study.

Purpose: We describe surgical outcomes in a single-surgeon, consecutive series of patients who received scleral buckle placement for primary retinal detachment using a modified external needle drainage technique.

Methods: Eighty-two eyes of 80 patients with primary retinal detachment underwent scleral buckle placement with modified external needle drainage. Preoperative, postoperative, and surgical data were collected.

Anti-inflammatory lipid mediator 15d-PGJ2 inhibits translation through inactivation of eIF4A.

The signaling lipid molecule 15-deoxy-delta 12,14-prostaglandin J2 (15d-PGJ2) has multiple cellular functions, including anti-inflammatory and antineoplastic activities. Here, we report that 15d-PGJ2 blocks translation through inactivation of translational initiation factor eIF4A. Binding of 15d-PGJ2 to eIF4A blocks the interaction between eIF4A and eIF4G that is essential for translation of many mRNAs.

Proline-rich transcript in brain protein induces stress granule formation.

The repression of translation in environmentally stressed eukaryotic cells causes the sequestration of translation initiation factors and the 40S ribosomal subunit into discrete cytoplasmic foci called stress granules (SGs). Most components of the preinitiation complex, such as eIF3, eIF4A, eIF4E, eIF4G, and poly(A)-binding protein, congregate into SGs under stress conditions. However, the molecular basis of translation factor sequestration into SGs has not been clearly elucidated.

A modified iris repair technique and capsular tension ring insertion in a patient with coloboma with cataracts.

Purpose: We describe our successful experience using a capsular tension ring (CTR) and iris repair during cataract surgery in a patient with bilateral coloboma.

Methods: A 67-year-old woman had no history of trauma, but had zonular deficiency and inferonasal iris defects in both eyes. An extracapsular cataract extraction and intraocular lens (IOL) scleral fixation was performed in the left eye.

Neovascularization in branch retinal vein occlusion combined with arterial insufficiency.

The aim of this study is to elucidate the association of neovascularization in branch retinal vein occlusion (BRVO) combined with major arterial insufficiency (MAI), compared with BRVO alone. The authors retrospectively reviewed the charts, color photographs, and fluorescein angiograms of 304 patients (308 eyes) who had BRVO from 1990 to 2002 at Hanyang University hospital. Patients with BRVO combined with MAI and patients with BRVO alone were differentiated by angiographic appearance.

Transscleral fixation of a dislocated IOL through sclerotomy.

We describe a technique for knotting a suture to the haptic of a dislocated intraocular lens (IOL) through a sclerotomy site without removing an IOL in 4 patients. The suture was knotted to the haptic from outside the sclera. The remaining suture material was tied together and buried in the sclerotomy site.