Enhanced cell adhesion to the dimpled surfaces of golf-ball-shaped microparticles.

Engineering surface morphology as in honeycomb-structured planar films is of great importance for providing new potential application and improved performance in biomedical fields. We demonstrate potential new applications for the uniform biocompatible golf-ball-shaped microparticles that resembles 3D feature of honeycomb-structured film. Dimple size controllable golf-ball-shaped microparticles were fabricated by microfluidic device.

Red meat consumption is associated with an increased overall cancer risk: a prospective cohort study in Korea.

Cancer is a leading cause of death, and the dietary pattern in Korea is changing rapidly from a traditional Korean diet to a Westernised diet. In the present study, we investigated the effects of dietary factors on cancer risk with a prospective cohort study. Among 26,815 individuals who participated in cancer screening examinations from September 2004 to December 2008, 8024 subjects who completed a self-administered questionnaire concerning demographic and lifestyle factors, and a 3 d food record were selected.

Predictive factors for extrathyroidal extension of papillary thyroid carcinoma based on preoperative sonography.

Objectives: The purpose of this study was to evaluate the diagnostic performance and predictive factors of extrathyroidal extension of papillary thyroid carcinoma based on preoperative sonography.

Methods: Preoperative sonography was performed for 568 patients who underwent surgery for papillary thyroid cancer between May 2009 and December 2010. Patients' T stages based on preoperative sonography were compared with their T stages based on pathologic examination, and we statistically analyzed the discriminatory performance of sonography.

Costs during the first five years following cancer diagnosis in Korea.

Objectives: We estimated the total medical costs incurred during the 5 years following a cancer diagnosis and annual medical use status for the six most prevalent cancers in Korea.

Methods: From January 1 to December 31, 2006, new patients registered with the six most prevalent cancers (stomach, liver, lung, breast, colon, and thyroid) were randomly selected from the Korea Central Cancer Registry, with 30% of patients being drawn from each cancer group. For the selected patients, cost data were generated using National Health Insurance claims data from the time of cancer diagnosis in 2006 to December 31, 2010.

Diffusion-weighted imaging of a prostate cancer xenograft model seen on a 7 Tesla animal MR scanner: comparison of ADC values and pathologic findings.

Objective: To assess the relationship between apparent diffusion coefficient (ADC) values on diffusion-weighted magnetic resonance (MR) imaging and pathologic measures of a tumor using a prostate cancer xenograft model.

Materials And Methods: Eighteen athymic nude mice with 36 PC-3-induced tumors were sacrificed to obtain specimens immediately after MR imaging in order to compare the findings on MR images with those seen on pathological specimens. Using a high-field small-animal MR scanner, T1- and T2-weighted imaging and DW MR imaging was performed.

Desmoplastic fibroma with malignant transformation.

Desmoplastic fibroma (DF) is a rare neoplasm of bone, showing infiltrative and locally aggressive nature. Here, we report a case of DF with an unusual histology arising in a 41-year-old female in the left distal femur, which was detected by plain x-ray as an osteolytic lesion and by magnetic resonance imaging as a well-demarcated mass with endosteal scalloping. Pathologically, the tumor was composed mainly of bland-looking spindle cells in abundant collagenous stroma, accompanied with areas of myxofibrosarcomatous and malignant fibrous histiocytomatous components.

Proton magnetic resonance spectroscopy of musculoskeletal lesions at 3 T with metabolite quantification.

Purpose: To evaluate whether proton MR spectroscopy (MRS) at 3 T with metabolite quantification is helpful for characterizing musculoskeletal lesions and to reveal whether the concentration of choline is correlated with the pathologic degree of malignancy.

Material And Methods: Three-tesla MR images and proton MRS data from 27 consecutive patients with surgically proven musculoskeletal lesions were retrospectively analyzed. We analyzed the presence of choline peaks of malignant tumors according to the degree of malignancies, and we compared them with those of benign lesions.

Nanoparticle assisted magnetic resonance imaging of the early reversible stages of amyloid beta self-assembly.

Co@Pt-Au nanoparticles, which have enhanced magnetism and high stability in aqueous media, are utilized in conjunction with MRI to monitor the structural evolution of Abeta assemblies, especially Abeta protofibrils in the early reversible stages.

Transient pulmonary eosinophilia incidentally found on low-dose computed tomography: findings in 40 individuals.

Purpose: To describe computed tomography (CT) findings of transient pulmonary eosinophilia (TPE) incidentally found on low-dose CT (LDCT) and to identify suggestive CT features helpful in initial diagnosis.

Materials And Methods: We retrospectively reviewed LDCT scans in 40 individuals who met criteria for having TPE. There were 35 men and 5 women (age range, 32-62 years; mean, 48.

Bronchial artery and systemic artery embolization in the management of primary lung cancer patients with hemoptysis.

Purpose: To assess the safety and effectiveness of arterial embolization in lung cancer patients with hemoptysis.

Methods: Nineteen primary lung cancer patients with hemoptysis underwent bronchial artery and systemic artery embolization from April 2002 to March 2005. There were 17 men and 2 women, with a mean age of 59 years.

CT findings of clear cell carcinoma of the ovary.

Purpose: The purpose of this article was to retrospectively evaluate computed tomographic (CT) findings in patients with pathologically proved clear cell carcinoma of the ovary.

Methods: CT scans of seven patients (age range, 28-79 years; mean age, 46 years) with nine lesions of histologically proved primary ovarian clear cell carcinoma of the ovary were retrospectively evaluated by two radiologists in consensus. Scans were evaluated for the laterality, size, mass characteristic, margin, attenuation of the cystic portion, internal architecture, and presence of lumen protruding mass.

MRI for pretreatment lymph node staging in uterine cervical cancer.

Objective: The purpose of this article is to assess the accuracy of MRI in detecting pelvic and paraaortic lymph node metastasis from uterine cervical cancer using various imaging criteria.

Conclusion: Although MRI analysis resulted in relatively low sensitivity, size and margin (spiculated or lobulated) were useful criteria for predicting lymph node metastasis from cervical cancer.

Contrast-enhanced CT for differentiation of ovarian metastasis from gastrointestinal tract cancer: stomach cancer versus colon cancer.

Objective: The purpose of our study was to determine whether the CT findings of ovarian metastasis from stomach cancer differ from those of ovarian metastasis from colon cancer.

Conclusion: On contrast-enhanced CT scans, ovarian metastatic lesions from stomach cancer appear more solid than, more frequently have dense enhancement of the solid portion, and are smaller than ovarian metastatic lesions from colon cancer.

Postbiopsy arterioportal fistula in patients with hepatocellular carcinoma: clinical significance in transarterial chemoembolization.

Objective: The purpose of this study was to determine, retrospectively, the frequency of postbiopsy arterioportal fistula in hepatocellular carcinoma and its significance in transarterial chemoembolization (TACE).

Materials And Methods: Forty-one patients who underwent percutaneous liver biopsy for diagnosis of hepatocellular carcinoma were referred for TACE. The control population comprised 161 patients referred during the same period who underwent TACE without biopsy.

Simple pulmonary eosinophilia evaluated by means of FDG PET: the findings of 14 cases.

Objective: We wanted to describe the findings of simple pulmonary eosinophilia with using 18 fluorodeoxyglucose (FDG) positron emission tomography (PET).

Materials And Methods: We analysed the findings of 14 patients who underwent thoracic computed tomography (CT) and PET, and then they were subsequently proven to have simple pulmonary eosinophilia. PET studies were performed in four patients with malignancy to evaluate for cancer metastasis, and PET scans were also done in 10 healthy subjects who underwent volunteer cancer screening.

Computed tomography findings of ovarian metastases from colon cancer: comparison with primary malignant ovarian tumors.

Objective: The computed tomography (CT) findings of ovarian metastases from colon cancer were evaluated and were compared with those of primary malignant ovarian tumors.

Methods: Sixteen patients with 21 masses from colon cancer and 20 patients with 31 primary malignant ovarian tumors were included in this study. The CT findings (laterality, size, margin, shape, mass characteristic, strong enhancement of cyst wall, enhancement of solid portion, amount of ascites, peritoneal seeding, lymph node enlargement, and metastasis) and ages of the patients in both groups were compared.

Single shot fast spin echo diffusion-weighted MR imaging of the spine; Is it useful in differentiating malignant metastatic tumor infiltration from benign fracture edema?

Purpose: This study aims to evaluate the usefulness of single shot fast spin echo diffusion-weighted MR imaging (DWSSFSE) in differentiating malignant metastatic tumor infiltration of vertebral bone marrow from benign vertebral fracture edema.

Materials And Methods: Forty-six consecutive patients with 59 acute osteoporotic or traumatic vertebral fractures (mean age = 59) and 31 patients with 98 vertebral metastasis including 20 pathologic fractures (mean age = 53) were included in this study. Diffusion-weighted MR images were obtained by single-shot fast spin echo technique with diffusion gradient (b = 500 s/mm2, TR/TE: 5002/99) by using a 1.