Publications by authors named "Joni Serlo"

Article Synopsis
  • The study investigated spine injuries in severely injured trauma patients (ISS/NISS > 15) over 15 years at a single trauma center in Helsinki.
  • It involved analyzing data from the Helsinki Trauma Registry, comparing patients with traumatic spine injuries to those without, and categorizing spine injuries by level and neurological symptoms.
  • Results showed that 53% of the patients had spine injuries, with high falls being the most common cause, especially among young women, while elderly patients typically experienced cervical spine injuries from low-energy accidents.
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Article Synopsis
  • The study assessed the long-term risk of total hip arthroplasty (THA) in patients who underwent in situ fixation for slipped capital femoral epiphysis (SCFE) over nearly 50 years.
  • Out of 138 patients, 41% had THA for hips treated for SCFE, with female patients and higher preoperative slip angles increasing their risk.
  • The results indicate that the risk of needing THA post-SCFE fixation is significantly higher than that of the general Finnish population, highlighting important predictive factors for clinicians.
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Article Synopsis
  • Residual tumors in patients treated for Ewing's sarcoma raise important clinical concerns, particularly regarding how different resection margins (nonviable vs. viable) affect patient outcomes.
  • A systematic review of relevant literature identified 45 articles to analyze the relationship between positive resection margins and 5-year survival rates, finding that both margin type and post-chemotherapy histological response are crucial for prognosis.
  • The review also suggests that radiation therapy can enhance local control for patients with poor surgical margins, highlighting a significant gap in current evidence that needs to be addressed for better patient care.
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Aim: Our aims were to establish the 10-year overall and event-free survival rates among children and adolescents with bone sarcomas in Finland, estimate their respective incidences, evaluate the treatment given and describe the key prognostic factors.

Methods: We included 88 patients of <18 years of age diagnosed with a bone sarcoma during 1991-2005 in this retrospective, nationwide and population-based study. Median follow-up time was 12.

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Background: Ewing's sarcoma family of tumors (ESFTs) are rare bone and soft tissue tumors characterized by specific genetic alterations. Our aim was to carry out a nationwide analysis of ESFT, to survey the treatments used and to report the five-year disease specific and event-free survival rates (EFS and DSS).

Material And Methods: The study data was gathered from the Finnish National Cancer Registry and all five University Hospitals and consisted of 76 bone and soft tissue ESFT patients diagnosed during 1990-2009.

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