Publications by authors named "Joni E Wright"
Article Synopsis
- The extracellular matrix, particularly the collagen-rich cuticle in nematodes, serves as a crucial barrier against environmental stressors, triggering defensive genetic responses when disrupted.
- Specific disruptions in cuticle collagen, especially at annular furrows, coactivate genes related to detoxification, osmotic stress, and antimicrobial defenses, indicating a unique signaling pathway.
- Key transcription factors like SKN-1/Nrf and ELT-3/GATA play essential roles in mediating these responses, suggesting a specialized damage-sensing mechanism tied to the cuticle's integrity.
