Improved gliotransmission by increasing intracellular Ca via TRPV1 on multi-walled carbon nanotube platforms.

Background: Astrocyte is a key regulator of neuronal activity and excitatory/inhibitory balance via gliotransmission. Recently, gliotransmission has been identified as a novel target for neurological diseases. However, using the properties of nanomaterials to modulate gliotransmission has not been uncovered.