Publications by authors named "Jonghak Lee"

A new tactile sensing module was proposed to sense the contact force and location of an object on a robot hand, which was attached on the robot finger. Three air pressure sensors are installed at the tip of the finger to detect the contacting force at the points. To obtain a nominal contact force at the finger from data from the three air pressure sensors, a force estimation was developed based upon the learning of a deep neural network.

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Background: The association of a higher body mass index (BMI) with better survival is a well-known "obesity paradox" in patients on hemodialysis (HD). However, men and women have different body compositions, which could impact the effect of BMI on mortality. We investigated the effect of gender on the obesity-mortality relationship in Korean patients on HD.

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Obesity is a well-established risk factor for cardiovascular disease (CVD), but the underweight population of body mass index (BMI) below 18.5 kg/m has not been an object of concern. The objective of this study is to investigate whether underweight could be an independent risk factor for CVD in a population-based cross-sectional study.

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Weather conditions are strongly correlated with traffic accident severity. In particular, rain-related factors are an important cause of traffic accidents due to the poor visibility and reduced friction resulting from slippery road conditions. This paper presents a systematic approach to analyze the extent to which the rainfall intensity and level of water depth are responsible for traffic accidents using Seoul City, Korea, as a case study.

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Administration of autologous mesenchymal stem cells (MSCs) has been shown to improve renal function and histological findings in acute kidney injury (AKI) models. However, its effects in chronic kidney disease (CKD) are unclear, particularly in the clinical setting. Here, we report our experience with a CKD patient who was treated by intravenous infusion of autologous MSCs derived from adipose tissue in an unknown clinic outside of Korea.

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Background/aims: There may be an association between vitamin D levels and allograft outcomes in kidney transplant recipients (KTRs). However, few studies have been conducted to determine the association between vitamin D levels and post-transplant infections. This study investigated the impact of vitamin D deficiency on the risk of infection after kidney transplantation.

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Background/aims: Little is known regarding the incidence rate of and factors associated with developing chronic kidney disease after continuous renal replacement therapy (CRRT) in acute kidney injury (AKI) patients. We investigated renal outcomes and the factors associated with incomplete renal recovery in AKI patients who received CRRT.

Methods: Between January 2011 and November 2013, 408 patients received CRRT in our intensive care unit.

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Background/aims: This study analyzed the risk factors for technique survival in dialysis patients and compared technique survival rates between hemodialysis (HD) and peritoneal dialysis (PD) in a prospective cohort of Korean patients.

Methods: A total of 1,042 patients undergoing dialysis from September 2008 to June 2011 were analyzed. The dialysis modality was defined as that used 90 days after commencing dialysis.

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Objective: Revascularization is critical for successful ovarian tissue transplantation. Vascular endothelial growth factor (VEGF) and angiopoietin-2 (angpt-2) are the principal mediators of neovascularization. This study was designed to assess VEGF and angpt-2 levels in cryopreserved ovarian tissue after heterotopic autotransplantation.

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Article Synopsis
  • Encapsulating peritoneal sclerosis (EPS) is a condition characterized by excessive fibrosis in the peritoneum of patients undergoing peritoneal dialysis, eventually resulting in complications like bowel obstruction.
  • The study evaluated the therapeutic effects of DNA demethylation via azacytidine treatment in a rat model of EPS, induced by chlorhexidine gluconate and ethanol, showing improved peritoneal conditions when treated.
  • Key findings included reduced thickness of the peritoneum, decreased levels of pro-fibrotic proteins (like TGF-β and α-SMA), and a reversal of RASAL1 hypermethylation, indicating that demethylation can alleviate EPS-related pathologies.
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Recurrence of focal segmental glomerulosclerosis (FSGS) is a major therapeutic challenge in kidney transplantation (KT). Although intensive plasmapheresis and high-dose rituximab have been introduced to treat recurrent FSGS, the most effective dosage and regimen of rituximab have not been determined. Herein we reported the first case of successful treatment of recurrent FSGS with a low-dose rituximab.

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Objective: To investigate the effect of the dimethyl sulfoxide (DMSO) and EFS-40 during vitrification on the expression of angiogenic factors in vitrified mouse ovarian tissue.

Methods: The ovarian tissues were obtained from 5 or 6 weeks aged ICR mouse. Ovarian tissues were divided into four groups: ovarian tissue without cryopreservation (control, group I), ovarian tissue vitrified with 15% DMSO (group II), ovarian tissue vitrified with EFS-40 (group III), and ovarian tissue slowly frozen with 10% DMSO (group IV).

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Hydrolysis of waste activated sludge (WAS) has been regarded as the rate limiting step of anaerobic sludge digestion. Therefore, in this study, the effect of ultrasound and hydraulic residence time during sludge hydrolysis was investigated with the goal of enhancing methane production from anaerobic digestion (AD). WAS was ultrasonically disintegrated for hydrolysis, and it was semi-continuously fed to an anaerobic digesters at various hydraulic retention times (HRTs).

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Article Synopsis
  • The study aimed to identify placental proteins linked to preeclampsia through proteomic analysis.
  • Using techniques like 2-D electrophoresis and MALDI-TOF-MS, researchers discovered twelve proteins with altered expression levels, highlighting Hsp27 as significantly upregulated.
  • The findings suggest that the elevated levels of Hsp27 could be related to the development of preeclampsia, with potential implications for understanding its underlying mechanisms.
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Novel monoclinic CuO nanobundles, 0.8-1 microm in size, were synthesized at 130 degrees C in the presence of sodium dodecyl benzenesulfonate (SDBS) by a simple hydrothermal method. Each nanobundle was comprised of many nanorods with one ends growing together to form a center and another ends radiating laterally from this center.

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A facile hydrothermal route has been developed for the synthesis of nearly spherical copper nanoparticles, copper nanocubes and ribbon-like network nanostructures. The as-prepared copper nanostructures were characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), transmission electron microscopy (TEM), high-resolution TEM (HRTEM), and UV-vis spectrum analysis. These copper products were fabricated in the presence of surfactant sodium dodecyl benzenesulfonate (SDBS) acting not only as stabilizer but also as size and shape controller via hydrothermal reduction process.

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Aims: Heat shock protein 27 (Hsp27) is a well-known stress response protein that is characterized by its phosphorylative capacity. Hsp27 becomes phosphorylated in response to various stimuli through interaction with several different kinases. The purpose of this study was to evaluate the interaction between Hsp27 and mitogen-activated protein kinase (MAPK) (p38, extracellular signal-regulated kinase [ERK], and c-Jun N-terminal kinase) in the human placenta derived from patients with pre-eclampsia.

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The effect of chemical oxygen demand/sulfate (COD/SO(4)(2-)) ratio on fermentative hydrogen production using enriched mixed microflora has been studied. The chemostat system maintained with a substrate (glucose) concentration of 15 g COD L(-1) exhibited stable H(2) production at inlet sulfate concentrations of 0-20 g L(-1) during 282 days. The tested COD/SO(4)(2-) ratios ranged from 150 to 0.

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Article Synopsis
  • A measurement scheme using tunable diode laser spectroscopy was developed to accurately detect water vapor concentrations, unaffected by scattering from non-water particles in a humidity chamber.
  • The technique measures relative water vapor concentration at a specific transition band using a 938 nm distributed feedback diode laser across various temperatures.
  • Experimental results demonstrate that the water vapor concentrations obtained are consistent and independent of the amount of scattering caused by dust particles.
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Article Synopsis
  • The study investigates the role of clusterin, a multifunctional protein, in normal and preeclamptic placental tissues, particularly its expression and localization.
  • Clusterin was found to be predominantly located in specific cells within the placenta and its levels were significantly higher in preeclamptic tissues compared to normal ones.
  • The findings suggest that elevated clusterin may be involved in the mechanisms underlying preeclampsia, indicating its potential significance in this condition.
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Aim: This study was designed to compare the survival rates, follicular growth rates, and ovulation rates of vitrified preantral follicles (PF) from ovaries with those isolated from a vitrified ovarian cortical strip.

Methods: Mouse ovaries were divided into three groups: those not treated by vitrification of the PF (control), those treated by vitrification of the PF isolated from the ovaries (group I), and those treated by vitrification of ovarian tissue followed by PF isolation (group II). The group I samples were exposed to equilibration solution (EG-20) for 5.

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