Topical tranexamic acid as an adjuvant treatment in melasma: Side-by-side comparison clinical study.

Background: Tranexamic acid (TNA) is a novel therapeutic agent for hyperpigmented skin disorders. The efficacy and safety of topical TNA in patients with melasma has not been heretofore studied. The main objective of this study is to evaluate the efficacy and safety of topical TNA combined with intense pulsed light (IPL) treatment in Asians with melasma.

Pulse in pulse intense pulsed light for melasma treatment: a pilot study.

Background: A new type of intense pulsed light IPL with pulse-in-pulse (PIP) mode (multiple fractionated subpulses in one pulse width) has recently been developed.

Objective: To evaluate the clinical efficacy and safety of PIP IPL in patients with melasma.

Materials And Methods: Half of each patient's face was treated with IPL and six treatment sessions with a low-fluence quality-switched neodymium-doped yttrium aluminum garnet laser (IPL/T) every 2 weeks.

Long-pulsed Nd:YAG laser on periorbital wrinkles in Asian patients: randomized split face study.

Background And Objective: This study evaluated clinical usefulness of long-pulsed Nd:YAG laser (LPNY) for periorbital wrinkles in Asian patients.

Methods: Twenty seven Korean patients were treated with several passes of LPNY (5 mm spot size, fluence: 54.7-61.