Wnt/beta-catenin signaling is crucial for developmental processes, particularly in melanocyte development.
Cardamonin, a compound derived from Aplinia katsumadai, inhibits pigmentation in melanocytes by blocking the Wnt/beta-catenin signaling pathway.
It reduces the expression of key factors involved in melanocyte differentiation, suggesting its potential as a whitening agent for cosmetic and medical applications in treating hyperpigmentation.