Publications by authors named "Jong-Phil Yang"

Background: Patients with diabetic foot commonly experience vascular insufficiency and compromised tissue perfusion. Extracorporeal shockwave therapy (ESWT) reportedly promotes wound healing and angiogenesis, but clinical studies on the effect of ESWT on angiogenesis are scarce and the exact mechanism remains unclear.

Objective: To investigate the effect of ESWT on cutaneous microcirculation in diabetic feet.

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Introduction: Maintaining adequate skin hydration is crucial in the feet of patients with diabetes because xerotic skin may crack and develop fissures, thereby increasing vulnerability to ulceration and infection. The nervous system is considered the powerhouse for maintaining adequate skin hydration; however, no clinical study has assessed the effect of the nervous system on skin hydration. In addition, it is hypothesized that microcirculation may play an important role in maintaining adequate hydration in patients with diabetes.

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Background: There are no studies about the treatment of nasal bone fractures in patients with dorsal augmentations using silicone implants. We aimed to describe the characteristics of nasal bone fracture in patients who underwent rhinoplasty and compare the difference between closed reduction and conservative treatment of nasal bone fractures in patients with a history of rhinoplasty.

Methods: Between January 2013 and June 2018, a total of 463 patients were admitted to our center for nasal bone fracture; 17 patients with nasal bone fractures who underwent rhinoplasty were included, of which, five underwent closed reduction in the nasal bone and 12 underwent conservative treatment.

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Article Synopsis
  • Aging is a biological process linked to functional declines and inflammatory reactions caused by oxidative stress, particularly from UV exposure, affecting skin cells differently based on timing and dosage of irradiation.
  • The study aimed to compare the effects of UV irradiation on cellular senescence in human epidermal keratinocytes (HaCaT) and dermal fibroblasts (HDFs), using various assays to measure cell viability and the production of reactive species.
  • Results showed decreased glutathione and increased nitrite levels in both cell types post-irradiation, with notable differences in inflammatory markers and proteins related to aging, particularly a more rapid response in HaCaT cells compared to HDFs.
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  • Percutaneous transluminal angioplasty (PTA) is commonly used to enhance blood flow in ischemic diabetic feet, but its effectiveness for severely ischemic cases was questioned.
  • A study involving 133 ischemic diabetic feet measured transcutaneous oxygen pressure (TcPO) and toe pressure before and after the PTA procedure, categorizing feet by ischemic severity.
  • Results showed that severely ischemic feet experienced the greatest improvement in blood perfusion post-PTA, indicating that PTA can effectively boost tissue perfusion even in challenging cases.
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Microvascular free flap transfer has become a prevailing surgery with a failure rate of <5%. However, pedicle thrombosis occurs more frequently than indicated by the failure rate. This difference is due to the successful salvage of failing flaps.

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