Initial local excision for clinical T1 rectal cancer showed comparable overall survival despite high local recurrence rate: a propensity-matched analysis.

Purpose: Local excision (LE) is an alternative initial treatment for clinical T1 rectal cancer, and has avoided potential morbidity. This study aimed to evaluate the clinical outcomes of LE compared with total mesorectal excision (TME) for clinical T1 rectal cancer.

Methods: Between January 2000 and December 2011, we retrospectively reviewed from multicenter data in patients with clinically suspected T1 rectal cancer treated with either LE or TME.

Preoperative endoscopic clipping for rectal tumor localization in laparoscopic anterior resection.

Increasing the number of rectal tumors undergoing preoperative chemoradiotherapy or endoscopic resection has increased the importance of accurate tumor localization. This study describes the preoperative endoscopic clipping method for the localization of rectal tumors and evaluated the feasibility of this technique. A total of 109 patients underwent preoperative endoscopic clipping to localize non-palpable rectal adenocarcinomas, which were located within 10 cm from the anal verge.

Lifestyle Factors and Bowel Preparation for Screening Colonoscopy.

Purpose: The quality of bowel preparation is a major determinant of the quality of colonoscopy. This study evaluated lifestyle factors, including usual dietary style, associated with bowel preparation.

Methods: This retrospective study evaluated 1,079 consecutive subjects who underwent complete colonoscopy from December 2012 to April 2014 at National Cancer Center of Korea.

Phase II Clinical Trial to Evaluate the Efficacy of Transanal Endoscopic Total Mesorectal Excision for Rectal Cancer.

Background: Total mesorectal excision has become the standard treatment for rectal cancer, and several investigators have shown that a transanal approach is a feasible option.

Objective: This study aimed to evaluate the efficacy of transanal endoscopic total mesorectal excision in patients with rectal cancer.

Design: This study was a prospective, single-arm phase II trial.

Histopathologic risk factors for lymph node metastasis in patients with T1 colorectal cancer.

Purpose: Evaluating the risk of lymph node metastasis (LNM) is critical for determining subsequent treatments following endoscopic resection of T1 colorectal cancer (CRC). This study analyzed histopathologic risk factors for LNM in patients with T1 CRC.

Methods: This study involved 745 patients with T1 CRC who underwent endoscopic (n = 97) or surgical (n = 648) resection between January 2001 and December 2015 at the National Cancer Center, Korea.

Risk of recurrence after endoscopic resection of early colorectal cancer with positive margins.

Background And Study Aim: Additional surgery is recommended if an endoscopically resected T1 colorectal cancer (CRC) specimen shows a positive resection margin. We aimed to investigate the significance of a positive resection margin in endoscopically resected T1 CRC.

Patients And Methods: We enrolled 265 patients with T1 CRC who underwent endoscopic resection between January 2001 and December 2016.

Magnetic Resonance Imaging-Detected Extramural Venous Invasion in Rectal Cancer before and after Preoperative Chemoradiotherapy: Diagnostic Performance and Prognostic Significance.

Objectives: We evaluated the diagnostic performance of magnetic resonance imaging (MRI) in terms of identifying extramural venous invasion (EMVI) in rectal cancer patients with preoperative chemoradiotherapy (CRT) and its prognostic significance.

Methods: During 2008-2010, 200 patients underwent surgery following preoperative CRT for rectal cancer. Two radiologists independently reviewed all pre- and post-CRT MRI retrospectively.

Correlation Between Bowel Preparation and the Adenoma Detection Rate in Screening Colonoscopy.

Purpose: The adenoma detection rate is commonly used as a measure of the quality of colonoscopy. This study assessed both the association between the adenoma detection rate and the quality of bowel preparation and the risk factors associated with the adenoma detection rate in screening colonoscopy.

Methods: This retrospective analysis involved 1,079 individuals who underwent screening colonoscopy at the National Cancer Center between December 2012 and April 2014.

Feasibility of transanal endoscopic total mesorectal excision for rectal cancer: results of a pilot study.

Purpose: To evaluate the feasibility of transanal total mesorectal excision (TME) in patients with rectal cancer.

Methods: This study enrolled 12 patients with clinically node negative rectal cancer located 4-12 cm from the anal verge who underwent transanal endoscopic TME with the assistance of single port laparoscopic surgery between September 2013 and August 2014. The primary endpoint was TME quality; secondary endpoints included number of harvested lymph nodes and postoperative complications within 30 days (NCT01938027).

A novel endoscopic fluorescent band ligation method for tumor localization.

Background: Accurate tumor localization is essential for minimally invasive surgery. This study describes the development of a novel endoscopic fluorescent band ligation method for the rapid and accurate identification of tumor sites during surgery.

Methods And Materials: The method utilized a fluorescent rubber band, made of indocyanine green (ICG) and a liquid rubber solution mixture, as well as a near-infrared fluorescence laparoscopic system with a dual light source using a high-powered light-emitting diode (LED) and a 785-nm laser diode.

Clinical impact of atypical endoscopic features in rectal neuroendocrine tumors.

Aim: To validate the association between atypical endoscopic features and lymph node metastasis (LNM).

Methods: A total of 247 patients with rectal neuroendocrine tumors (NETs) were analyzed. Endoscopic images were reviewed independently by two endoscopists, each of whom classified tumors by sized and endoscopic features, such as shape, color, and surface change (kappa coefficient 0.

Outcomes of pelvic exenteration for recurrent or primary locally advanced colorectal cancer.

Purpose: The objective of this study was to assess the clinical outcomes of pelvic exenteration for patients with primary locally advanced colorectal cancer (LACRC) or locally recurrent colorectal cancer (LRCRC), and to identify clinically relevant prognostic factors.

Methods: Between January 2001 and December 2010, 40 consecutive patients with primary LACRC or LRCRC underwent pelvic exenteration at the National Cancer Center, Republic of Korea. We retrospectively reviewed their medical records.

The role of fibrinogen as a predictor in preoperative chemoradiation for rectal cancer.

Background: To perform chemoradiotherapy (CRT) effectively, it is clinically beneficial to identify predictors of tumor response after CRT. This study examined the association between plasma fibrinogen level before preoperative CRT and tumor response in advanced rectal cancer.

Methods: This was a retrospective study of 947 patients who received preoperative CRT followed by curative surgery for primary rectal cancer.

Hybrid surgery versus percutaneous mechanical thrombectomy for the thrombosed hemodialysis autogenous arteriovenous fistulas.

Purpose: For the successful treatment of thrombosed autogenous arteriovenous fistula (AVF), we designed and performed a hybrid surgery. Its clinical outcomes were compared with those of percutaneous mechanical thrombectomy, retrospectively.

Methods: Forty cases of thrombosed autogenous AVFs underwent hybrid surgery, whereas 19 cases received percutaneous mechanical thrombectomy.