Probiotic Ln4 Showing Antimicrobial and Antibiofilm Effect against KCTC 5124 Causing Dental Caries.

Dental caries has known as an infectious disease that is considered a serious global public health problem. Recently, report indicate that probiotics play a vital role in maintaining oral health. Therefore, this study aimed to evaluate the prevention effects of Ln4 against dental infection by the pathogenic bacterium KCTC 5124 through biofilm formation inhibition.

Clinical Comparison of Keratitis according to the Initial Potassium Hydroxide (KOH) Smear: A Retrospective Study in South Korea.

Purpose: This study aimed to compare predisposing factors, clinical characteristics, treatment, and prognosis of keratitis according to the result of the initial potassium hydroxide (KOH) smear.

Methods: This is a retrospective study of cases with keratitis between January 2000 and December 2019 at two tertiary hospitals in South Korea. Patients were divided into two groups depending on the KOH smear result (KOH-positive and KOH-negative group), and its clinical factors were analyzed.

Physicochemical analysis of non-fermented probiotic milk with probiotic Ln1 isolated from Korea traditional fermented food.

The objective of this study was to develop a non-fermented probiotic milk that maintains its physicochemical properties, microbial properties, antioxidant activity, and sensory properties during storage (0, 7, and 14 days). During storage, pH and viable cell counts decreased; however, titratable acidity increased. In addition, the composition and sensory characteristics of the non-fermented probiotic milk showed no significant differences between samples (MLN; milk with Ln1, MGG; milk with GG, and milk control).

Optimization of an Industrial Medium and Culture Conditions for Probiotic JW15 Biomass Using the Plackett-Burman Design and Response Surface Methodology.

The objective of this study was to optimize industrial-grade media for improving the biomass production of JW15 (JW15) using a statistical approach. Eleven variables comprising three carbon sources (glucose, fructose, and sucrose), three nitrogen sources (protease peptone, yeast extract, and soy peptone), and five mineral sources (KHPO, potassium citrate, L-cysteine phosphate, MgSO, and MnSO) were screened by using the Plackett-Burman design. Consequently, glucose, sucrose, and soy peptone were used as significant variables in response surface methodology (RSM).

Antibacterial and Antibiofilm Effect of Cell-Free Supernatant of KCCM 202399 Isolated from Korean Fermented Food against KCTC 5458.

This study aims to determine the antibiofilm effect of cell-free supernatant (CFS) of strains against strains. To study the antibiofilm mechanism against strains, antibacterial effects, cell surface properties (auto-aggregation and cell surface hydrophobicity), exopolysaccharide (EPS) production, and morphological changes were examined. The antibiofilm effect of KCCM 202399 CFS as morphological changes were evaluated by scanning electron microscopy (SEM) and confocal laser scanning microscopy (CLSM), compared with the control treatment.

Inhibitory effects of Lactobacillus brevis KU15153 against Streptococcus mutans KCTC 5316 causing dental caries.

This study determined the inhibitory effect of Lactobacillus brevis KU15153 against cariogenic Streptococcus mutans KCTC 5316. Antimicrobial activity, auto-aggregation, cell surface hydrophobicity, exopolysaccharides (EPS) production, biofilm formation, and morphological changes were assessed in the presence of L. brevis KU15153.

The Influence of Users' Spatial Familiarity on Their Emotional Perception of Space and Wayfinding Movement Patterns.

In order to evaluate the sensory perceptions of users who visited a train station, this study aimed to conduct an evaluation of their spatial emotions and identify the distance and type of transfer. For evaluation and verification, emotional recognition and wayfinding types were analyzed according to types in the groups (gender, age, and spatial familiarity) of experimental participants. There were two research questions: "Will the length of movement patterns in the experiment environment vary depending on the types of the participant group?" and "Is there any moderating effect in the interaction between spatial familiarity and the types of the participant groups?" A total of 28 participants were recruited with consideration of gender, age, and familiarity with spatial experience, which were used to analyze the participant groups.

Recurrent hemoptysis in a 26-year-old woman with a ground-glass opacity lesion of the lung.

Hemoptysis is a major reason for emergency department (ED) visits. Catamenial hemoptysis (CH), a rare condition of thoracic endometriosis, can cause recurrent hemoptysis but is difficult to diagnose in the ED due to the scarcity of cases and nonspecific clinical findings. We report a case of a 26-year-old woman who presented to the ED with recurrent hemoptysis since 2 years without a definite cause.

Splenic artery aneurysm with the double-rupture phenomenon.

Splenic artery aneurysm is the third most common type of intra-abdominal aneurysm, with a prevalence rate of 0.01% to 10.4% in the general population.

Newly identified paired box 6 mutation of variant familial aniridia: Congenital iris ectropion with foveal hypoplasia.

Congenital aniridia is a kind of eye disease characterized by complete or partial hypoplasia of the iris and is associated with other ocular anomalies including corneal opacity, glaucoma, and foveal hypoplasia. Heterozygous mutation of paired box 6 (PAX6) gene was identified in most cases of aniridia, with iatrogenic mutations accounting for about two-third of the cases and chromosomal rearrangements accounting for the other one-third. We report rare cases of variant aniridia, congenital iris ectropion associated with foveal hypoplasia in both a woman and her son with a mutation of PAX6 gene.

Effect of Acanthopanax senticosus stem on mast cell-dependent anaphylaxis.

We studied the effect of Acanthopanax senticosus stem (ACPS) on mast cell-dependent anaphylaxis. ACPS inhibited compound 48/80-induced systemic anaphylaxis at a dose of 1.0 g/kg by 50%.