Glycolipids Derived from the Korean Endemic Plant Inducing Glucose Uptake in Mouse Skeletal Muscle C2C12 Cells.

spp. has been used as a traditional folk medicine worldwide for its anti-inflammatory, hemostatic, and detoxifying properties. The well-known species var.

Saponins Derived from the Korean Endemic Plant Inhibit Diffuse-type Gastric Cancer Cells.

Diffuse-type gastric cancer (GC) is a type of stomach cancer that occurs in small clusters of cells that are widely spread. It does not typically manifest with symptoms until the advanced stages and often goes undetected in routine imaging tests. In addition, there is no specific targeted therapy for diffuse-type GC and it has a high mortality risk.

Ecdysteroids from the Korean Endemic Species with Activities against Glucocorticoid Receptors and 11β-Hydroxysteroid Dehydrogenase Type 1.

Two new ecdysteroids, spectasterone A () and spectasterone B (), together with four known ecdysteroids, breviflorasterone (), ajugalactone (), 20-hydroxyecdysone (), and polypodine B () were isolated from the Korean endemic plant using feature-based molecular networking analysis. The chemical structures of and were determined based on the interpretation of NMR and mass spectrometric data. Their absolute configurations were established using coupling constants, NOESY interactions, Mosher's method, and ECD and DP4+ calculations.

Chemical constituents isolated from Actinidia polygama and their α-glucosidase inhibitory activity and insulin secretion effect.

Actinidia polygama has been used as a traditional medicine for treating various diseases. In the present study, 13 compounds, including three new monoterpenoids (1-3), were isolated from the leaves of A. polygama to investigate the bioactive constituents of the plant.