Publications by authors named "Jong Baek Lim"
Article Synopsis
- The study focused on determining reference intervals for serum insulin-like growth factor 1 (IGF-1) and IGFBP-3, which are crucial for diagnosing growth hormone-related disorders in children.
- Researchers reviewed the serum levels of IGF-1 and IGFBP-3 in healthy Korean children aged 0-17, using various immunoassay methods to gather data for establishing reference intervals.
- The results showed that the reference percentiles for IGF-1 and IGFBP-3 are influenced by the immunoassay method used and highlight the importance of considering age and sex when determining these intervals for accurate assessments.
The timely diagnosis and therapeutic monitoring of human renal cell carcinoma (RCC) is limited by the lack of specific biomarkers. To identify candidate RCC biomarkers, we used 2-DE gel electrophoresis with mass spectrometry and 2-DE spot intensity-based ROC analysis to analyze 18 sets of paired normal and RCC tumor tissue including conventional, papillary, and chromophobe subtypes. Validation was performed with RCC patient plasma samples and confirmed by clustergram, shRNA, and immunohistochemistry assays.
View Article and Find Full Text PDFConcentration of cytokines in age-related macular degeneration after consecutive intravitreal bevacizumab injection.
Graefes Arch Clin Exp Ophthalmol
May 2010
Background: To evaluate the changes in aqueous humor cytokine levels following consecutive intravitreal bevacizumab (Avastin, Genentech Inc., San Francisco, CA, USA) injections in eyes with choroidal neovascularization (CNV) due to age-related macular degeneration (AMD).
Method: Aqueous humor samples were collected at the time of intravitreal injection of 1.
Purpose: : To evaluate the concentration of various cytokines in the aqueous humor of patients with naive, recurrent, and regressed choroidal neovascularization (CNV) of age-related macular degeneration after bevacizumab treatment.
Methods: : Aqueous humor samples were collected from 36 eyes with age-related macular degeneration and 10 controls during cataract surgery. Of 36 patients with age-related macular degeneration, 5 eyes were naïve to bevacizumab injection, 14 eyes had recurrent CNV after bevacizumab treatment, and 17 eyes had regressed CNV after bevacizumab treatment.
Purpose: To determine the effect of intravitreal bevacizumab (Avastin, Genentech, Inc., San Francisco, CA) injection on aqueous humor cytokine levels in clinically significant macular edema (CSME).
Design: Retrospective, comparative study.