Crystal structures of six complexes of phosphane chalcogenides P ( = -butyl or isopropyl, = S or Se) with the metal halides ( = Pd or Pt, = Cl or Br), two halochalcogenyl-phospho-nium derivatives ( Bu PrPBr)[PdBr] and one hydrolysis product.

The complexes - (: = BuPrPSe, = Pd, = Cl; : = Bu PrPSe, = Pd, = Cl; : = Bu PrPSe, = Pd, = Br; : = Bu PrPS, = Pd, = Br; : = Bu PrPS, = Pt, = Cl) {systematic names: (-butyl-diiso-propyl-phosphine selenide-κ)di-chlorido-palladium(II), [PdCl(CHPSe)] (), (di--butyl-iso-propyl-phosphine selenide-κ)di-chloridopalladium(II), [PdCl(CHPSe)] (), di-bromido-(di--butyl-iso-propyl-phosphine selenide-κ)palladium(II), [PdBr(CHPSe)] (), di-bromido-(di--butyl-iso-propyl-phosphine sulfide-κ)palladium(II), [PdBr(CHPS)] (), di-chlorido-(di--butyl-iso-propyl-phosphine sulfide-κ)palladium(II), [PdCl(CHPS)] ()} all display a configuration with square-planar geometry at the metal atom. Compounds and are isotypic. The mol-ecules of and display crystallographic inversion symmetry; compound involves two independent mol-ecules, each with inversion symmetry but with differing orientations of the tri-alkyl-phosphane groups.

Epilepsy Risk Associated With the Receipt of General Anesthesia Relative to Neuraxial Anesthesia: A Retrospective Cohort Study.

Background And Objectives: Evidence suggests that the receipt of general anesthesia may be associated with an increased risk of epilepsy compared with neuraxial (i.e., spinal or epidural) anesthesia.

Chronic Viral Hepatitis Screening Inequities Across Florida Federally Qualified Health Centers.

Aim: Examine racial and ethnic inequities in hepatitis C and B virus (HCV and HBV) screening across high-risk populations.

Subject And Methods: Chronic HCV and HBV infections can lead to cirrhosis, hepatocellular carcinoma (HCC), and death. Despite universal screening recommendations, < 50% of US adults are tested for these viruses.

Physical and Match Characteristics of English Elite Academy Soccer Players: Differences Between Age Groups.

Dickinson, B, Jones, P, and Comfort, P. Physical and match characteristics of English elite academy soccer players: differences between age groups. J Strength Cond Res XX(X): 000-000, 2024-The purpose of this study was to evaluate physical and match characteristics of elite academy soccer players and determine differences between age groups.

Search for Magnetic Monopole Pair Production in Ultraperipheral Pb+Pb Collisions at sqrt[s_{NN}]=5.36 TeV with the ATLAS Detector at the LHC.

This Letter presents a search for highly ionizing magnetic monopoles in 262  μb^{-1} of ultraperipheral Pb+Pb collision data at sqrt[s_{NN}]=5.36  TeV collected by the ATLAS detector at the LHC. A new methodology that exploits the properties of clusters of hits reconstructed in the innermost silicon detector layers is introduced to study highly ionizing particles in heavy-ion data.

Measuring the clinical dimensions of negative symptoms through the Positive and Negative Syndrome Scale.

The negative symptoms of schizophrenia can determine functional outcome in patients. Despite its clinical significance, no treatment exists to date, as numerous pharmacological and non-pharmacological clinical trials have failed to demonstrate efficacy. Many of these trials evaluated negative symptoms as a single clinical construct.

Impact of sleep on postpartum health outcomes: a systematic review and meta-analysis.

Objective: To examine the impact of postpartum sleep interventions and postpartum sleep on maternal health outcomes.

Design: Systematic review with random-effects meta-analysis. Online databases were searched on 12 January 2024.

Impact of postpartum physical activity on maternal sleep: a systematic review and meta-analysis.

Objective: To examine the relationship between postpartum physical activity and maternal sleep.

Design: Systematic review with random-effects meta-analysis. Online databases were searched through 20 January 2025.

MEDTEG (Minimum Entropy Dynamic Test Grids): A Novel Algorithm for Adding New Test Locations to a Perimetric Test Grid.

Purpose: To describe a novel algorithm (MEDTEG) for dynamically adding new test locations to a perimetric grid-to provide a more personalized/comprehensive visual field (VF) assessment.

Methods: MEDTEG operates by finding the most informative new test location. First, Voronoi tessellation is used to construct a list of candidate locations (i.

Evaluating the Appropriate Use Criteria for Coronary Revascularization in Stable Ischemic Heart Disease Using Randomized Data From the ISCHEMIA Trial.

Background: The appropriate use criteria for revascularization of stable ischemic heart disease have not been evaluated using randomized data. Using data from the randomized ISCHEMIA trial (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches; July 2012 to January 2018, 37 countries), the health status benefits of an invasive strategy over a conservative one were examined within appropriate use criteria scenarios.

Methods: Among 1833 participants mapped to 36 appropriate use criteria scenarios, symptom status was assessed using the Seattle Angina Questionnaire-7 at 1 year for each scenario and for each of the 6 patient characteristics used to define the scenarios.

Secreted IgM deficiency alters the retinal landscape enhancing neurodegeneration associated with aging.

Background: Maintenance of the retina, part of the central nervous system, and other structures in the eye is critical for vision preservation. Aging increases the prevalence of vision impairment, including glaucoma, macular degeneration, and diabetic retinopathy. The retina is primarily maintained by glial cells; however, recent literature suggests that lymphocytes may play a role in the homeostasis of central nervous system tissues.

Gene therapy in children with AIPL1-associated severe retinal dystrophy: an open-label, first-in-human interventional study.

Background: Retinal dystrophy caused by genetic deficiency of AIPL1 causes severe and rapidly progressive impairment of sight from birth. We sought to evaluate whether early intervention by gene supplementation therapy was safe and could improve outcomes in children with this condition.

Methods: This non-randomised, single-arm, clinical study conducted in the UK involved four children aged 1·0-2·8 years with severe retinal dystrophy associated with biallelic disease-causing sequence variants in AIPL1.

Predictors of Right Ventricular Pacing in Patients Undergoing Implantable Defibrillator Placement.

Introduction: Identifying patients who will develop a need for right ventricular (RV) pacing after defibrillator (ICD) placement would help inform appropriate device selection, specifically to identify patients who might be more suitable for dual chamber or biventricular transvenous defibrillators versus single-chamber or subcutaneous devices which do not provide pacing. We sought to determine predictors of RV pacing in patients who did not have a pacing indication at the time of initial ICD implant.

Methods: This observational study assessed single-chamber ICD recipients implanted from 2006 to 2016 from Boston Scientific's ALTITUDE database and linked to the NCDR® ICD Registry.

Performance of an active fixation stylet-driven lead in left bundle branch area pacing: Results from INSIGHT-LBBA.

Background: Left bundle branch area pacing (LBBAP) has been rapidly adopted despite a lack of leads with approved indications for LBBAP.

Objective: This study aims to analyze the performance of a 6Fr active fixation, stylet-driven lead in LBBAP.

Methods: The multicenter INSIGHT-LBBA registry analyzed consecutive LBBAP implant attempts with INGEVITY+ leads.

Crystal structures of six miscellaneous products arising from the oxidation of precursors PAu ( = -butyl or isopropyl; = S or Se; = Cl, Br or I).

Compound , (disulfane-1,2-di-yl)bis-(-butyl-diiso-propyl-phospho-nium) bis-[tetra-chlorido-aurate(III)], ( Bu PrP)S·[AuCl], contains the first structurally characterized dication of the form {( P) } . The ions are linked by S⋯Cl contacts and C-H⋯Cl hydrogen bonds to form ribbons of residues parallel to the axis. Compound is bis-(di--butyl-iso-propyl-phosphine sulfide-κ)gold(I) triiodide/di-iodido-aurate(I)(0.

Cognitive presentation at psychosis onset through premorbid deterioration and exposure to environmental risk factors.

Background: Previous studies identified clusters of first-episode psychosis (FEP) patients based on cognition and premorbid adjustment. This study examined a range of socio-environmental risk factors associated with clusters of FEP, aiming a) to compare clusters of FEP and community controls using the Maudsley Environmental Risk Score for psychosis (ERS), a weighted sum of the following risks: paternal age, childhood adversities, cannabis use, and ethnic minority membership; b) to explore the putative differences in specific environmental risk factors in distinguishing within patient clusters and from controls.

Methods: A univariable general linear model (GLS) compared the ERS between 1,263 community controls and clusters derived from 802 FEP patients, namely, low (n = 223) and high-cognitive-functioning (n = 205), intermediate (n = 224) and deteriorating (n = 150), from the EU-GEI study.

A qualitative study exploring the feasibility and acceptability of computerised adaptive testing to assess and monitor children and young people's mental health in primary care settings in the UK.

Background: The increasing prevalence of mental health disorders among adolescents highlights the importance of early identification and intervention. Artemis-A is a web-based application of computerised adaptive testing (CAT), originally developed for secondary schools, to quickly and efficiently assess students' mental health. Due to its speed, reliability and accessibility, it may be a valuable tool for healthcare practitioners (HCPs) working with children and young people (CYP) in primary, community and potentially secondary care settings in the future.

Distribution and correlates of long-acting injectable antipsychotic use among community mental health center patients.

Although long-acting injectable antipsychotics (LAIs) are an important pharmaceutical option in the management of schizophrenia and related disorders, little is known about patient characteristics related to LAI use in real-world outpatient settings. We analyzed electronic medical records from 41,401 patients who received psychiatric services from one of 16 regional mental health centers operated by the South Carolina Department of Mental Health in 2022. We compared the use of first- and second-generation LAIs and oral antipsychotics by sociodemographic (age, gender, race/ethnicity, zip code, payment source) and clinical characteristics (psychiatric diagnoses, service use).

Simultaneous Unbinned Differential Cross-Section Measurement of Twenty-Four Z+jets Kinematic Observables with the ATLAS Detector.

Z boson events at the Large Hadron Collider can be selected with high purity and are sensitive to a diverse range of QCD phenomena. As a result, these events are often used to probe the nature of the strong force, improve Monte Carlo event generators, and search for deviations from standard model predictions. All previous measurements of Z boson production characterize the event properties using a small number of observables and present the results as differential cross sections in predetermined bins.

Understanding the Mechanism of Electrochemical CO Capture by Supercapacitive Swing Adsorption.

Carbon dioxide capture underpins an important range of technologies that can help to mitigate climate change. Improved carbon capture technologies that are driven by electrochemistry are under active development, and it was recently found that supercapacitor energy storage devices can reversibly capture and release carbon dioxide. So-called supercapacitive swing adsorption (SSA) has several advantages over traditional carbon dioxide capture technologies such as lower energy consumption and the use of nontoxic materials.

Silver N-Heterocyclic Biscarbene Complexes: Potent Inhibitors of Thioredoxin Reductase with Anticancer Activity in Vitro and in Vivo.

Silver N-heterocyclic carbene (NHC) complexes are known to form biscarbene species from monocarbene analogs in protic polar solvents. However, the effect of the respective species of silver NHC complexes on their biological activity against bacteria or cancer cells has not been systematically explored, either in vitro or in vivo. The direct and simple conversion of monocarbene silver N-heterocyclic carbene (NHC) halide complexes (NHC)AgX, (X=Cl, Br) 1 a/b-5 a/b to their biscarbene analogues (NHC)AgX 1 c/d-5 c/d is reported.

Defining the Cost of Arthroscopic Rotator Cuff Repair: A Multicenter, Time-Driven Activity-Based Costing and Cost Optimization Investigation.

Background: Rotator cuff repair (RCR) is a frequently performed outpatient orthopaedic surgery, with substantial financial implications for health-care systems. Time-driven activity-based costing (TDABC) is a method for nuanced cost analysis and is a valuable tool for strategic health-care decision-making. The aim of this study was to apply the TDABC methodology to RCR procedures to identify specific avenues to optimize cost-efficiency within the health-care system in 2 critical areas: (1) the reduction of variability in the episode duration, and (2) the standardization of suture anchor acquisition costs.

Precision psychiatry: thinking beyond simple prediction models - enhancing causal predictions.

Making informed clinical decisions based on individualised outcome predictions is the cornerstone of precision psychiatry. Prediction models currently employed in psychiatry rely on algorithms that map a statistical relationship between clinical features (predictors/risk factors) and subsequent clinical outcomes. They rely on associations that overlook the underlying causal structures within the data, including the presence of latent variables, and the evolution of predictors and outcomes over time.

Validity and Inter-Device Reliability of an Artificial Intelligence App for Real-Time Assessment of 505 Change of Direction Tests.

The present study aimed to explore the validity and inter-device reliability of a novel artificial intelligence app (Asstrapp) for real-time measurement of the traditional (tra505) and modified-505 (mod505) change of direction (COD) tests. Twenty-five male Sports Science students (age, 23.5 ± 3.

Markedly Elevated Citrulline in a Neonate: Citrin Deficiency due to a Previously Unreported Solute Carrier Family 25 Member 13 Variant.

Background: Citrin deficiency (CD) is an autosomal recessive metabolic disorder affecting the urea cycle and energy production. Diagnosis involves measuring ammonia and amino acid levels (eg: citrulline), with confirmation through solute carrier family 25 member 13 (SLC25A13) gene mutation analysis. Herein, we present a case report of a variant in the SLC25A13 gene that has not been previously reported in the literature.