[Blepharoplasty after tumor ("cancer eye") removal from the eyes of cattle].

A literature review of surgical techniques used for resection of periocular tumors with conservation of the eyelid is accompanied by a report of the author's personal experience with blepharoplasty in cattle. Included are 13 cases of Fleckvieh cows with squamous cell carcinoma. Five animals were without tumor recurrence after an average time of 10.

["Cancer eye" in German spotted cattle. Occurrence, treatment methods and results].

Incidence, therapy and outcome of bovine ocular squamous cell carcinoma are reported on the basis of 128 cases seen in Fleckvieh cows over a period of 15 years. Of the cases observed, 112 were treated surgically. Of 70 patients checked between 6 and 31 months post op.

Ultrastructural changes in the liver following chronic experimental intoxication with benzine and ethyline vapour.

The livers of two groups of rabbits exposed to longer lasting intoxication, one with benzine vapours and the other one with ethyline vapours, were subjected to examination in an electron microscope twice; immediately after the completion of intoxication and then 3 months later. In both groups there were found: dilatation of the perinuclear spaces, a symptom of nucleolus segregation, dilatation of the ergastoplasm, features of cristolysis of mitochondria and the absence of glycogen. These changes were more intensive in the animals intoxicated with ethyline.

Ultrastructural changes in the lungs after chronic experimental intoxication with benzine and ethyline vapour.

In the group of rabbits chronically intoxicated with petrol vapour slight changes in the dust cells of lungs in the form of cytoplasmic vacuolisation and accumulation of collagen almost completely disappeared 3 months after intoxication. Changes in animals intoxicated with ethyline were much more severe. Besides the accumulation of collagen, appearance of elastin areas, cytolysosomes, changes in the nucleus, widening of ergastoplasm, swelling and cristolysis of mitochondria were observed.

Histochemical and histoenzymatic changes in mouse liver in subacute benzene intoxication.

The investigations were performed on mice. They were divided into a control group and 4 experimental groups. The experimental animals were administered intraperitoneally benzene 6 X every 24 h.

The behaviour of some enzymes in the mouse liver due to chronic benzene intoxication.

1. Long trem benzene action brings about a permanent decrease in oxidoreductive enzymes and active transport as well as an inactivation of the lysosomal apparatus in liver-cells. 2.

Demonstration of glycocalyx in the sweat gland.

Skin specimens were taken without any anaesthesia from four volunteers before and after a 1 hour's exposure to heat. No glycocalyx could be demonstrated in the resting gland, but it usually appeared, however, after one hour of thermal sweating--although not in all the sections. The possible implication of this phenomenon is briefly discussed and new problems outlined.

Quantitative determination of acid phosphatase activity detected in tissue sections according to the Burstone method.

Quantitative determination of the activity of acid phosphatase detected in tissue sections using Burstone's method. The experiment was performed on inbred rats. A reaction for AcP according to Burstone was made in liver sections, incubation time was fixed experimentally.

The effect of 35SO2 binding by ammonia on sulfur incorporation into rat tissues.

Sulfur metabolism was traced in experimental investigations on rats, and the importance of the method of sulfur dioxide neutralized by ammonia was estimated. The animals were exposed to 35SO2 by means of inhalation, and radioactivity in several organs at different periods of exposure was traced. Apart from that, autoradiographic investigations were carried out in order to show the incorporation of radioactive sulfur into particular elements of the cell in different tissues.

[Effect of phenobarbital stimulation on morphological and cytoenzymatic changes in the liver of benzene intoxicated rats (author's transl)].

The experiments were carried out on male Wistar-Rats. They were divided into 2 groups. The rats of the control groups were treated to Phenobarbital intraperitoneally for 3 consecutive days.

The effect of 5-fluorouracil on the mitotic cycle and DNA synthesis in the epithelium of mouse small intestine.

The examinations were performed on 42 mice of the Porton strain. The experimental animals were injected intraperitoneally with the dose of 75 mg of 5-fluorouracil per kg body weight. The first experimental group received injections of [3H]thymidine within 48 hours and the second group within 96 hours of the injection of 5-fluorouracil.

Histoenzymatic changes in the dog kidney in an experimentally induced crushing injury of the thorax.

The experiments were carried out on dogs. Experimental animals were subjected to the trauma of the thorax during operation. The localization and activity of succinic dehydrogenase, NADH2-tetrazole reductase, adenosine triphosphatase, alkaline and acid phosphates in the kidneys were examined.

The dynamics of histoenzymatic changes in the kidney in acute poisoning with benzene.

The experiments were carried out in mice which were divided into 4 experimental groups and a control group. In the course of the experiment SD, NADH2-tetrazolium reductase; ATP-ase, G-6-P-ase and AP were observed. It was found that acute benzene intoxication causes the disturbances in the enzymatic activities of the cells of the main segment of the nephron.