Publications by authors named "Jonathan T Paul"
Study Design: Preclinical animal study.
Objective: Evaluate the osteoinductivity and bone regenerative capacity of BioRestore bioactive glass.
Summary Of Background Data: BioRestore is a Food and Drug Administration (FDA)-approved bone void filler that has not yet been evaluated as a bone graft extender or substitute for spine fusion.
Article Synopsis
- - This study explored how male and female rats respond differently to a specific bone healing treatment (rhBMP-2) in spinal fusion surgery, addressing a gap in existing research on sex-based effects of this treatment.
- - After eight weeks, it was found that female rats had lower manual fusion scores but a higher bone volume fraction compared to males, though their overall fusion mass volume was smaller.
- - While both sexes showed similar stiffness in bone healing, female rats exhibited a greater range of motion, suggesting distinct biomechanical responses related to sex in the context of bone regeneration.
Objectives: To compare the estimated resource utilization for non-operative treatment of cervical radiculopathy if managed by surgeons versus non-surgeons.
Patients And Methods: A Cervical Spine Research Society-sponsored survey was administered at a national spine surgery conference to surgeons and non-surgeons, as classified above. The survey asked questions regarding resource utilization and perceived costs for the "average patient" with cervical radiculopathy managed non-operatively.
The Effect of Dynamic Versus Static Plating Systems on Fusion Rates and Complications in 1-Level and/or 2-Level Anterior Cervical Discectomy and Fusion: A Systematic Review.
Clin Spine Surg
February 2017
Study Design: A systematic review.
Objective: To determine the effect of plate design on fusion rates in patients undergoing a 1- and 2-level anterior cervical discectomy and fusion (ACDF).
Methods: Articles published between January 1, 2002 and January 1, 2015 were systematically reviewed to determine the fusion rate of 1- and 2-level ACDFs using either a fully constrained or semiconstrained locking plate.
Background: Odontoid fractures are the most common cervical spine fracture in the geriatric population; however, the treatment of type II odontoid fractures in this age group is controversial.
Objective: To compare the short-term (<3 months) mortality, long-term (≥12 months) mortality, and complication rates of patients >60 years of age with a type II odontoid fracture managed either operatively or nonoperatively.
Methods: We performed a systematic review of literature published between January 1, 2000, and February 1, 2015, related to the treatment of type II odontoid fractures in patients >60 years of age.