Publications by authors named "Jonathan Ryan Burris"
Article Synopsis
- - The study investigates how the absence of cyclophilin D (CypD) affects mitochondrial function during heart development by comparing wildtype and CypD knockout mice from embryonic day 9.5 to adulthood.
- - Findings reveal that CypD deletion modifies the timing of mitochondrial activity transitions and keeps the mitochondrial permeability transition pore (mPTP) closed throughout development, impacting energy production and metabolic processes.
- - The results imply that adjusting CypD levels could influence heart cell growth and function, potentially serving as a strategy to enhance ATP production and overall cardiac performance in developing hearts.
